The role of dorsal raphe nucleus serotonergic and non-serotonergic neurons, and of their receptors, in regulating waking and rapid eye movement (REM) sleep

JM Monti - Sleep medicine reviews, 2010 - Elsevier
Based on electrophysiological, neurochemical, genetic and neuropharmacological
approaches it is currently accepted that serotonin (5-HT) functions to promote waking (W) …

Anatomical organization of the melanin-concentrating hormone peptide family in the mammalian brain

JC Bittencourt - General and comparative endocrinology, 2011 - Elsevier
More than 20 years ago, melanin-concentrating hormone (MCH) and its peptide family
members–neuropeptide EI (NEI) and neuropeptide GE (NGE)–were described in various …

The δ isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload

J Backs, T Backs, S Neef… - Proceedings of the …, 2009 - National Acad Sciences
Acute and chronic injuries to the heart result in perturbation of intracellular calcium
signaling, which leads to pathological cardiac hypertrophy and remodeling …

Melanin-concentrating hormone neurons discharge in a reciprocal manner to orexin neurons across the sleep–wake cycle

OK Hassani, MG Lee, BE Jones - Proceedings of the …, 2009 - National Acad Sciences
Neurons containing melanin-concentrating hormone (MCH) are codistributed with neurons
containing orexin (Orx or hypocretin) in the lateral hypothalamus, a peptide and region …

Hypocretin (orexin) cell loss in Parkinson's disease

TC Thannickal, YY Lai, JM Siegel - Brain, 2007 - academic.oup.com
It has recently been reported that Parkinson's disease (PD) is preceded and accompanied
by daytime sleep attacks, nocturnal insomnia, REM sleep behaviour disorder, hallucinations …

The melanin-concentrating hormone as an integrative peptide driving motivated behaviors

GB Diniz, JC Bittencourt - Frontiers in systems neuroscience, 2017 - frontiersin.org
The melanin-concentrating hormone (MCH) is an important peptide implicated in the control
of motivated behaviors. History, however, made this peptide first known for its participation in …

Effects on sleep of melanin-concentrating hormone (MCH) microinjections into the dorsal raphe nucleus

P Lagos, P Torterolo, H Jantos, MH Chase, JM Monti - Brain research, 2009 - Elsevier
Neurons that utilize melanin-concentrating hormone (MCH) as a neuromodulator are
located in the lateral hypothalamus and incerto-hypothalamic area, and project diffusely …

Melanin-concentrating hormone (MCH): role in REM sleep and depression

P Torterolo, C Scorza, P Lagos… - Frontiers in …, 2015 - frontiersin.org
The melanin-concentrating hormone (MCH) is a peptidergic neuromodulator synthesized by
neurons of the lateral sector of the posterior hypothalamus and zona incerta. MCHergic …

Blocking melanin-concentrating hormone MCH1 receptor affects rat sleep–wake architecture

A Ahnaou, WHIM Drinkenburg, JA Bouwknecht… - European journal of …, 2008 - Elsevier
Melanin-concentrating hormone (MCH) is a hypothalamic peptide that centrally regulates
food intake, energy balance and emotion. Interestingly, MCH and melanin-concentrating …

Sleep-wake neurobiology

G Vanini, P Torterolo - … and Sleep: Molecular, Functional and Clinical …, 2021 - Springer
Sleep and wakefulness are complex, tightly regulated behaviors that occur in virtually all
animals. With recent exciting developments in neuroscience methodologies such as …