Euthyroid sick syndrome

S Lee, AP Farwell - Comprehensive Physiology, 2011 - Wiley Online Library
In this review, we discuss the characteristics, pathophysiology, and therapeutic implications
of the euthyroid sick syndrome. Multiple mechanisms have been identified to contribute to …

Effects of thyroid hormone on tissue hypoxia: relevance to sepsis therapy

AI Lourbopoulos, IS Mourouzis, AG Trikas… - Journal of Clinical …, 2021 - mdpi.com
Tissue hypoxia occurs in various conditions such as myocardial or brain ischemia and
infarction, sepsis, and trauma, and induces cellular damage and tissue remodeling with …

Analysis of the incidence of euthyroid sick syndrome in comprehensive intensive care units and related risk factors

J Guo, Y Hong, Z Wang, Y Li - Frontiers in endocrinology, 2021 - frontiersin.org
Objective A low concentration of plasma triiodothyronine (T3) indicates euthyroid sick
syndrome (ESS), which could be associated with a poor outcome in patients in intensive …

[HTML][HTML] The non-thyroidal illness syndrome

LJ DeGroot - Endotext [Internet], 2015 - ncbi.nlm.nih.gov
ABSTRACT NTIS refers to a syndrome found in seriously ill or starving patients with low fT3,
usually elevated RT3, normal or low TSH, and if prolonged, low fT4. It is found in a high …

Disruption of thyroid hormone regulated proteins and gene expression by polychlorinated biphenyls, polybrominated diphenyl ethers and new flame retardants in …

LC Guo, S Yu, D Wu, J Huang, T Liu, J Xiao… - Environmental …, 2019 - Elsevier
Polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs) and new flame
retardants (NFRs) are known thyroid hormone (TH) disruptors, but their disrupting …

Thyroid hormones regulate both cardiovascular and renal mechanisms underlying hypertension

SS Jankauskas, MB Morelli… - The Journal of …, 2020 - pmc.ncbi.nlm.nih.gov
Physiologically, thyroid hormones are able to affect the fundamental determinants of blood
pressure (BP): cardiac output, peripheral vascular resistance, and kidney function (Figure 1) …

[PDF][PDF] Role of the thyroid system in myelination and neural connectivity

L Calza, M Fernández, L Giardino - Comprehensive Physiology, 2015 - researchgate.net
The role of thyroid hormone on brain development is dramatically illustrated by “cretinism,” a
severe mental retardation due to iodine deficiency and maternal hypothyroidism during …

[HTML][HTML] Physiological responses of growing pigs to high ambient temperature and/or inflammatory challenges

PHRF Campos, L Floc'h, J Noblet… - Revista Brasileira de …, 2017 - SciELO Brasil
Global warming is one of the major environmental threats facing the world in the 21st
century. This fact will have a significant impact on pig production due to its direct effects on …

[HTML][HTML] Moderate SIRT1 overexpression protects against brown adipose tissue inflammation

C Escalona-Garrido, P Vázquez, P Mera, S Zagmutt… - Molecular …, 2020 - Elsevier
Objective Metainflammation is a chronic low-grade inflammatory state induced by obesity
and associated comorbidities, including peripheral insulin resistance. Brown adipose tissue …

Lipopolysaccharide (LPS)-induced septic shock causes profound changes in myocardial energy metabolites in pigs

J Lado-Abeal, N Martinez-Sánchez, JA Cocho… - Metabolomics, 2018 - Springer
Introduction Energy deficiency is a cause for myocardial dysfunction during septic shock. In
rodents, septic shock decreases the oxidation of long-chain fatty acids and glucose in the …