DNA-based copy number analysis confirms genomic evolution of PDX models
ACH Hoge, M Getz, A Zimmer, M Ko, L Raz… - NPJ Precision …, 2022 - nature.com
Genomic evolution of patient-derived xenografts (PDXs) may lead to their gradual
divergence away of their tumors of origin. We previously reported the genomic evolution of …
divergence away of their tumors of origin. We previously reported the genomic evolution of …
Discovery of Genetic Vulnerabilities in NRAS-Mutant Melanoma
AY Gu - 2023 - researchspace.auckland.ac.nz
New Zealand has the highest incidence of malignant melanoma in the world. Specifically,
melanoma with NRAS mutations are of particular clinical concern due to its association with …
melanoma with NRAS mutations are of particular clinical concern due to its association with …