The discovery of neuronal systems dedicated to computing spatial information, composed of
functionally distinct cell types such as place and grid cells, combined with an extensive body …

Aging affects many aspects of everyday living, such as autonomy, security and quality of life.
Among all, spatial memory and spatial navigation show a gradual but noticeable decline, as …

The gastrointestinal tract is abundantly colonized by microbes, yet the translocation of oral
species to the intestine is considered a rare aberrant event, and a hallmark of disease. By …

The entorhinal cortex is one of the first regions to exhibit neurodegeneration in Alzheimer's
disease, and as such identification of entorhinal cortex dysfunction may aid detection of the …

Virtual reality environments presented on tablets and smartphones have potential to aid the
early diagnosis of conditions such as Alzheimer's dementia by quantifying impairments in …

Much of our understanding of navigation comes from the study of individual species, often
with specific tasks tailored to those species. Here, we provide a novel experimental and …

Spatial navigation is a complex cognitive process based on multiple senses that are
integrated and processed by a wide network of brain areas. Previous studies have revealed …

Introduction Spatial navigation, which involves higher cognitive functions, is frequently
implemented in daily activities, and is critical to the participation of human beings in …

A progressive loss of navigational abilities in old age has been observed in numerous
studies, but we have only limited understanding of the neural mechanisms underlying this …

Efficient spatial navigation requires not only accurate spatial knowledge but also the
selection of appropriate strategies. Using a novel paradigm that allowed us to distinguish …