Naphthalimide derivatives with therapeutic characteristics: A patent review
A Kamal, NR Bolla, PS Srikanth… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Naphthalimides are important aromatic heterocycles with immense
pharmacological significance as they serve as core scaffold for many antitumor, anti …
pharmacological significance as they serve as core scaffold for many antitumor, anti …
1, 8‐Naphthalimide: a potent DNA intercalator and target for cancer therapy
The poor pharmacokinetics, side effects and particularly the rapid emergence of drug
resistance compromise the efficiency of clinically used anticancer drugs. Therefore, the …
resistance compromise the efficiency of clinically used anticancer drugs. Therefore, the …
Overview of naphthalimide analogs as anticancer agents
M Lv, H Xu - Current medicinal chemistry, 2009 - ingentaconnect.com
Cancer, which accounted for 7.9 million deaths (around 13% of all deaths) in 2007, is a
leading cause of death in the world. Deaths from cancer worldwide are projected to continue …
leading cause of death in the world. Deaths from cancer worldwide are projected to continue …
Synthesis and activities of naphthalimide azoles as a new type of antibacterial and antifungal agents
YY Zhang, CH Zhou - Bioorganic & medicinal chemistry letters, 2011 - Elsevier
Naphthalimide-derived azoles as a new type of antimicrobial agents were synthesized and
evaluated for their efficiency in vitro against eight bacteria and two fungi by two fold serial …
evaluated for their efficiency in vitro against eight bacteria and two fungi by two fold serial …
Naphthalimides in fluorescent imaging of tumor hypoxia–An up-to-date review
Hypoxia is a distinctive characteristic of advanced solid malignancies that results from a
disparity between oxygen supply and its consumption. The degree of hypoxia is believed to …
disparity between oxygen supply and its consumption. The degree of hypoxia is believed to …
A series of naphthalimide azoles: Design, synthesis and bioactive evaluation as potential antimicrobial agents
GLV Damu, QP Wang, HZ Zhang, YY Zhang… - Science China …, 2013 - Springer
A series of naphthalimide azoles as potential antibacterial and antifungal agents were
conveniently and efficiently synthesized starting from commercially available 6-bromobenzo …
conveniently and efficiently synthesized starting from commercially available 6-bromobenzo …
Novel lead compounds in pre-clinical development against African sleeping sickness
M Berninger, I Schmidt, A Ponte-Sucre… - MedChemComm, 2017 - pubs.rsc.org
Human African trypanosomiasis (HAT), also known as African sleeping sickness, is caused
by parasitic protozoa of the genus Trypanosoma. As the disease progresses, the parasites …
by parasitic protozoa of the genus Trypanosoma. As the disease progresses, the parasites …
Simultaneous staining of endoplasmic reticulum and lipid droplets by naphthol-aminonaphthalimide conjugates and photoinduced antiproliferative effects
M Sambol, M Košćak, L Uzelac, M Kralj, I Piantanida… - Dyes and pigments, 2022 - Elsevier
A detailed study of photophysical properties and photochemical reactivity of five novel
naphthol-aminonaphthalimide conjugates 1a-1e (differing in the linker length between two …
naphthol-aminonaphthalimide conjugates 1a-1e (differing in the linker length between two …
Synthesis, molecular modeling study, preliminary antibacterial, and antitumor evaluation of N-substituted naphthalimides and their structural analogues
Carboxylic acid imides 1–26 have been synthesized and screened for their antibacterial
against gram-positive and gram-negative organisms and their antitumor activity against 60 …
against gram-positive and gram-negative organisms and their antitumor activity against 60 …
Copper (I) complexes with quinolone appended 1, 8-naphthalimide conjugates: structural characterization, DNA and protein binding and cytotoxicity studies
A novel 1, 8-naphthalimide containing ligand (L) and its three mononuclear complexes with
different anions,[Cu (L) 2](NO3)· 3 (H2O)(1),[Cu (L) 2] Cl· 4 (H2O)(2),[Cu (L) 2] ClO4· DMF (3) …
different anions,[Cu (L) 2](NO3)· 3 (H2O)(1),[Cu (L) 2] Cl· 4 (H2O)(2),[Cu (L) 2] ClO4· DMF (3) …