Glutamate serves as both the mammalian brain's primary excitatory neurotransmitter and as
a key neuromodulator to control synapse and circuit function over a wide range of spatial …

In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

The mammalian ionotropic glutamate receptor family encodes 18 gene products that
coassemble to form ligand-gated ion channels containing an agonist recognition site, a …

The ionotropic glutamate receptors are ligand-gated ion channels that mediate the vast
majority of excitatory neurotransmission in the brain. The cloning of cDNAs encoding …

The N-methyl D-aspartate (NMDA) receptor subtype of glutamate-gated ion channels
possesses high calcium permeability and unique voltage-dependent sensitivity to …

L-glutamate, the principal excitatory transmitter in the brain, gates ion channels mediating
fast neurotransmission. Subunit components of two related classes of glutamate receptor …

The glutamate receptors mediate excitatory neurotransmission in the brain and are
important in memory acquisition, learning, and some neurodegenerative disorders. This …

The detection of odorant receptor mRNAs within the axon terminals of sensory neurons has
permitted us to ask whether neurons expressing a given receptor reject their axons to …

The AMPA receptor, which is involved in most fast glutamatergic transmission in the
mammalian brain and is expressed in most neurons, is made up of four subunits, GluR1–4 …

A complementary DNA encoding the rat NMDA receptor has been cloned and characterized.
The single protein encoded by the cDNA forms a receptor-channel complex that has …