Animal models of major depression: drawbacks and challenges

B Planchez, A Surget, C Belzung - Journal of Neural Transmission, 2019 - Springer
Major depression is a leading contributor to the global burden of disease. This situation is
mainly related to the chronicity and/or recurrence of the disorder, and to poor response to …

[HTML][HTML] The cafeteria diet: A standardized protocol and its effects on behavior

JF Lalanza, EMS Snoeren - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Obesity is a major health risk, with junk food consumption playing a central role in weight
gain, because of its high palatability and high-energy nutrients. The Cafeteria (CAF) diet …

Long-term effects of chronic stress models in adult mice

I Tran, AK Gellner - Journal of neural transmission, 2023 - Springer
Neuropsychiatric disorders, such as major depression, anxiety disorders, and post-traumatic
stress disorder, tend to be long-term conditions in whose development and maintenance …

Stress in groups: lessons from non-traditional rodent species and housing models

AK Beery, MM Holmes, W Lee, JP Curley - Neuroscience & Biobehavioral …, 2020 - Elsevier
A major feature of life in groups is that individuals experience social stressors of varying
intensity and type. Social stress can have profound effects on health, social behavior, and …

[HTML][HTML] The social instability stress paradigm in rat and mouse: A systematic review of protocols, limitations, and recommendations

A Koert, A Ploeger, CLH Bockting, MV Schmidt… - Neurobiology of …, 2021 - Elsevier
Background Social stress is an important environmental risk factor for the development of
psychiatric disorders, including depression and anxiety disorders. Social stress paradigms …

Pharmacological characterisation of the effort for reward task as a measure of motivation for reward in male mice

C Marangoni, M Tam, ESJ Robinson, MG Jackson - Psychopharmacology, 2023 - Springer
Rationale Motivational deficits are a common symptom shared across multiple psychiatric
and neurodegenerative disorders. Effort-based decision-making tasks are a translatable …

Operant social self-administration in male CD1 mice

SS Lee, M Venniro, Y Shaham, BT Hope… - …, 2024 - Springer
Abstract Rationale and Objective We recently introduced a model of operant social reward in
which female CD1 mice lever press for access to affiliative social interaction with a …

[HTML][HTML] The effectiveness of anti-inflammatory agents in reducing chemotherapy-induced cognitive impairment in preclinical models–A systematic review

OJ Haller, I Semendric, RP George… - Neuroscience & …, 2023 - Elsevier
Chemotherapy-induced cognitive impairment (CICI) is a debilitating condition resulting from
chemotherapy administration for cancer treatment. CICI is characterised by various cognitive …

Perfused rat term placenta as a preclinical model to investigate placental dopamine and norepinephrine transport

H Horackova, V Vachalova, C Abad… - Clinical …, 2023 - portlandpress.com
The placenta represents a non-neuronal organ capable of transporting and metabolizing
monoamines. Since these bioactive molecules participate in numerous processes essential …

CtBP Neuroprotective Role in Toxin-Based Parkinson's Disease Models: From Expression Pattern to Dopaminergic Survival

C Saraiva, J Lopes-Nunes, M Esteves, T Santos… - Molecular …, 2023 - Springer
C-terminal binding proteins (CtBP) are transcriptional co-repressors regulating gene
expression. CtBP promote neuronal survival through repression of pro-apoptotic genes, and …