Inhibition of BRD4 prevents proliferation and epithelial–mesenchymal transition in renal cell carcinoma via NLRP3 inflammasome-induced pyroptosis
YF Tan, M Wang, ZY Chen, L Wang, XH Liu - Cell death & disease, 2020 - nature.com
BRD4 has long been implicated in many different pathological processes, in particular, the
development of cancer and inflammation. Pyroptosis is a newly recognized type of …
development of cancer and inflammation. Pyroptosis is a newly recognized type of …
[HTML][HTML] The molecular mechanism of NF-κB dysregulation across different subtypes of renal cell carcinoma
Background The nuclear factor kappa B (NF-κB) is a critical pathway that regulates various
cellular functions, including immune response, proliferation, growth, and apoptosis …
cellular functions, including immune response, proliferation, growth, and apoptosis …
Mutational analysis of PBRM1 and significance of PBRM1 mutation in anti-PD-1 immunotherapy of clear cell renal cell carcinoma
A Aili, J Wen, L Xue, J Wang - Frontiers in Oncology, 2021 - frontiersin.org
Renal cell carcinoma is a common solid tumor. PBRM1 is one of the most mutation-prone
genes in clear cell renal cell carcinoma (ccRCC) with the occurrence of mutation in 40% of …
genes in clear cell renal cell carcinoma (ccRCC) with the occurrence of mutation in 40% of …
Integrative analysis reveals CRHBP inhibits renal cell carcinoma progression by regulating inflammation and apoptosis
K Yang, Y Xiao, T Xu, W Yu, Y Ruan, P Luo… - Cancer Gene …, 2020 - nature.com
Patients with renal cell carcinoma (RCC) usually develop drug resistance and have poor
prognosis owing to its insensitive property. However, the underlying mechanisms of RCC …
prognosis owing to its insensitive property. However, the underlying mechanisms of RCC …
[HTML][HTML] Silencing hTERT attenuates cancer stem cell-like characteristics and radioresistance in the radioresistant nasopharyngeal carcinoma cell line CNE-2R
K Chen, L Li, S Qu, X Pan, Y Sun, F Wan, B Yu… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Objective: This study aimed to explore the effect of silencing hTERT on the CSC-like
characteristics and radioresistance of CNE-2R cells. Results: Silencing hTERT suppressed …
characteristics and radioresistance of CNE-2R cells. Results: Silencing hTERT suppressed …
Silencing of nuclear factor kappa b 1 gene expression inhibits colony formation, cell migration and invasion via the downregulation of interleukin 1 beta and matrix …
LFS Teixeira, JPS Peron, MH Bellini - Molecular Biology Reports, 2020 - Springer
Renal cell carcinoma (RCC) is a highly deadly urological tumor due to its high metastatic
incidence and its notorious chemoresistance. The nuclear transcription factor kappa B (NF …
incidence and its notorious chemoresistance. The nuclear transcription factor kappa B (NF …
Avaliação da capacidade angiogênica da linhagem celular de adenocarcinoma renal humano knockout para a proteína NF-kB1
LFT Silva - 2021 - teses.usp.br
O carcinoma de células renais (CCR) é o câncer epitelial renal adulto mais comum, sendo
responsável por mais de 90% de todas as neoplasias renais. O subtipo mais frequente de …
responsável por mais de 90% de todas as neoplasias renais. O subtipo mais frequente de …
[PDF][PDF] Variations in Essential Elements After Malignant Transformation of Kidney Epithelial Tubular Cells
MH Bellini, AL de Souza, FF da Silva, SN Guilhen… - repositorio.ipen.br
Cell line-based research is a valuable tool for the study of cancer physiopathology and the
discovery of new drugs for use in clinical practice. In this study, inductively coupled plasma …
discovery of new drugs for use in clinical practice. In this study, inductively coupled plasma …