[HTML][HTML] Micronucleus assay: the state of art, and future directions

S Sommer, I Buraczewska, M Kruszewski - International journal of …, 2020 - mdpi.com
During almost 40 years of use, the micronucleus assay (MN) has become one of the most
popular methods to assess genotoxicity of different chemical and physical factors, including …

The HUman MicroNucleus project on eXfoLiated buccal cells (HUMNXL): The role of life-style, host factors, occupational exposures, health status, and assay protocol

S Bonassi, E Coskun, M Ceppi, C Lando… - … Research/Reviews in …, 2011 - Elsevier
The human buccal micronucleus cytome assay (BMCyt) is one of the most widely used
techniques to measure genetic damage in human population studies. Reducing protocol …

Heavy metals and human health

S Morais, FG Costa, ML Pereira - Environmental health–emerging …, 2012 - books.google.com
Metals occur naturally in the earth's crust, and their contents in the environment can vary
between different regions resulting in spatial variations of background concentrations. The …

[HTML][HTML] Combined toxic exposures and human health: biomarkers of exposure and effect

I Silins, J Högberg - International journal of environmental research and …, 2011 - mdpi.com
Procedures for risk assessment of chemical mixtures, combined and cumulative exposures
are under development, but the scientific database needs considerable expansion. In …

The HUMN and HUMNxL international collaboration projects on human micronucleus assays in lymphocytes and buccal cells—past, present and future

M Fenech, N Holland, E Zeiger, WP Chang… - …, 2011 - academic.oup.com
Abstract The International Human Micronucleus (HUMN) Project (www. humn. org) was
founded in 1997 to coordinate worldwide research efforts aimed at using micronucleus (MN) …

Clinical application of micronucleus test in exfoliated buccal cells: A systematic review and metanalysis

C Bolognesi, S Bonassi, S Knasmueller… - … research/reviews in …, 2015 - Elsevier
The micronucleus assay in uncultured exfoliated buccal mucosa cells, involving minimally
invasive sampling, was successfully applied to evaluate inhalation and local exposure to …

Occupational exposure to formaldehyde and early biomarkers of cancer risk, immunotoxicity and susceptibility

S Costa, C Costa, J Madureira, V Valdiglesias… - Environmental …, 2019 - Elsevier
Formaldehyde (FA) is a high-volume production chemical manufactured worldwide to which
many people are exposed to both environmentally and occupationally. FA was recently …

Micronuclei, inflammation and auto-immune disease

M Kirsch-Volders, C Bolognesi, M Ceppi… - … Research/Reviews in …, 2020 - Elsevier
Auto-immune diseases (AUD) are characterized by an immune response to antigenic
components of the host itself. The etiology of AUD is not well understood. The available …

Use of the lymphocyte cytokinesis-block micronucleus assay in occupational biomonitoring of genome damage caused by in vivo exposure to chemical genotoxins …

A Nersesyan, M Fenech, C Bolognesi, M Mišík… - … Research/Reviews in …, 2016 - Elsevier
This article concerns the use of the lymphocyte cytokinesis-block micronucleus (CBMN)
assay in biomonitoring of occupational and environmental exposures to genotoxic agents …

Genetic damage in coal miners evaluated by buccal micronucleus cytome assay

G León-Mejía, M Quintana, R Debastiani, J Dias… - Ecotoxicology and …, 2014 - Elsevier
During coal mining activities, large quantities of coal dust, ashes, polycyclic aromatic
hydrocarbons and metals are released into the environment. This complex mixture presents …