40 years after the registration of acyclovir: do we need new anti-herpetic drugs?

A Majewska, B Mlynarczyk-Bonikowska - International journal of …, 2022 - mdpi.com
Herpes simplex virus types 1 and 2 HSV1 and 2, namely varicella-zoster VZV and
cytomegalovirus CMV, are among the most common pathogens worldwide. They remain in …

CRISPR/Cas system: a potential technology for the prevention and control of COVID-19 and emerging infectious diseases

R Ding, J Long, M Yuan, Y Jin, H Yang… - Frontiers in cellular …, 2021 - frontiersin.org
The continued global pandemic of coronavirus disease 2019 (COVID-19) poses a serious
threat to global public health and social stability and it has become a serious global public …

Structural basis for HCMV Pentamer receptor recognition and antibody neutralization

M Kschonsak, MC Johnson, R Schelling, EM Green… - Science …, 2022 - science.org
Human cytomegalovirus (HCMV) represents the viral leading cause of congenital birth
defects and uses the gH/gL/UL128-130-131A complex (Pentamer) to enter different cell …

COVID‐19 associated EBV reactivation and effects of ganciclovir treatment

M Meng, S Zhang, X Dong, W Sun… - Immunity …, 2022 - Wiley Online Library
Abstract Background Systemic reactivation of Epstein–Barr virus (EBV) may occur in novel
coronavirus disease 2019 (COVID‐19) caused by the severe acute respiratory syndrome …

Strigolactones, from plants to human health: achievements and challenges

V Dell'Oste, F Spyrakis, C Prandi - Molecules, 2021 - mdpi.com
Strigolactones (SLs) are a class of sesquiterpenoid plant hormones that play a role in the
response of plants to various biotic and abiotic stresses. When released into the …

Plant-derived antimicrobial peptides as potential antiviral agents in systemic viral infections

N Mammari, Y Krier, Q Albert, M Devocelle… - Pharmaceuticals, 2021 - mdpi.com
Numerous studies have led to a better understanding of the mechanisms of action of viruses
in systemic infections for the development of prevention strategies and very promising …

Challenges, recent advances and perspectives in the treatment of human cytomegalovirus infections

SJ Chen, SC Wang, YC Chen - Tropical Medicine and Infectious Disease, 2022 - mdpi.com
Human cytomegalovirus (HCMV) is ubiquitous worldwide and elicits global health problems.
The diseases associated with HCMV are a serious threat to humans, especially for the sick …

Infection, rejection, and the connection

LE Higdon, JC Tan, JS Maltzman - Transplantation, 2023 - journals.lww.com
Solid organ transplantation is a life-saving treatment for people with end-stage organ
disease. Immune-mediated transplant rejection is a common complication that decreases …

[HTML][HTML] Insight for immunotherapy of HCMV infection

X Long, Y Qiu, Z Zhang, M Wu - International journal of biological …, 2021 - ncbi.nlm.nih.gov
Human cytomegalovirus (HCMV), a ubiquitous in humans, has a high prevalence rate.
Young people are susceptible to HCMV infection in developing countries, while older …

Targeting CMV reactivation to optimize care for critically Ill COVID-19 patients: a review on the therapeutic potential of antiviral treatment

G Schinas, V Moustaka, E Polyzou, MP Almyroudi… - Viruses, 2023 - mdpi.com
Cytomegalovirus (CMV) reactivation has been linked to adverse clinical outcomes in
critically ill patients, with emerging evidence suggesting a potential connection with severe …