Systematic review aims to systematically identify, critically appraise, and summarize all
relevant studies that match predefined criteria and answer predefined questions. The most …

OBJECTIVE Predicting neurological recovery following traumatic spinal cord injury (TSCI) is
a complex task considering the heterogeneous nature of injury and the inconsistency of …

Importance A previous meta-analysis of the association between alcohol use and all-cause
mortality found no statistically significant reductions in mortality risk at low levels of …

Publication bias is a serious problem in systematic reviews and meta-analyses, which can
affect the validity and generalization of conclusions. Currently, approaches to dealing with …

Background: Emerging reports suggest that new onset of smell or taste loss are potential
early clinical markers of SARS-CoV-2 infection, but it remains unclear as to what extent …

Study Design. Method guideline for systematic reviews of trials of interventions for neck and
back pain, and related spinal disorders. Objective. To help authors design, conduct, and …

Background Systematic reviews and meta-analyses of observational studies are frequently
performed, but no widely accepted guidance is available at present. We performed a …

Objectives To summarise the evidence about the efficacy of a Mediterranean diet on the
management of type 2 diabetes and prediabetic states. Design A systematic review of all …

Background Meta-analyses frequently include studies with small sample sizes. Researchers
usually fail to account for sampling error in the reported within-study variances; they model …

The systematic review of evidence is the research method which underpins the traditional
approach to evidence-based healthcare. There is currently no uniform methodology for …