Cancer is one of the leading causes of death globally, around 10 million deaths are reported
every year due to cancer. Some clinically approved anticancer drugs play a riveting role in …

Amongst heterocyclic compounds, quinoline and its derivatives are advantaged scaffolds
that appear as a significant assembly motif for developing new drug entities. Aminoquinoline …

Cancer is one of the leading causes of death. Globally a huge number of deaths and new
incidences are reported annually. Heterocyclic compounds have been proved to be very …

Targeted therapy plays a pivotal role in cancer therapeutics by countering the drawbacks of
conventional treatment like adverse events and drug resistance. Over the last decade …

Cancer will directly affect the lives of over one-third of the population. The DNA Damage
Response (DDR) is an intricate system involving damage recognition, cell cycle regulation …

The BRCA1 is a tumor suppressor gene that encodes for the BRCA1 protein, which plays a
vital role in DNA repair, cell cycle regulation, and the maintenance of genomic stability. The …

Genomic instability is one of the hallmarks of cancer. The incidence of genetic alterations in
homologous recombination repair genes increases during cancer progression, and 20% of …

A new series of 2‐aminobenzothiazole derivatives was designed, synthesized and
evaluated for their anticancer activity against the MCF7, MDAMB‐231, and HepG2 cancer …

Background Tyrosine phosphorylation of intracellular proteins is a post‐translational
modification that plays a regulatory role in signal transduction during cellular events …

A validated HPTLC method was developed for simultaneous quantification of rhein and
emodin: two anthraquinones with diverse bioactivities in Cassia fistula (C. fistula) leaves …