Tuberculosis (TB) is a serious global public health challenge that results in significant
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …

A past history of pulmonary tuberculosis (TB) is a risk factor for long-term respiratory
impairment. Post-TB lung dysfunction often goes unrecognised, despite its relatively high …

The major innate immune cell types involved in tuberculosis (TB) infection are
macrophages, dendritic cells (DCs), neutrophils and natural killer (NK) cells. These immune …

Background The adaptive immune response in rheumatoid arthritis (RA) is influenced by an
interaction between host genetics and environment, particularly the host microbiome …

Chemokines and cytokines are critical for initiating and coordinating the organized and
sequential recruitment and activation of cells into Mycobacterium tuberculosis-infected …

Infection with Mycobacterium tuberculosis causes> 1.5 million deaths worldwide annually.
Innate immune cells are the first to encounter M. tuberculosis, and their response dictates …

Nitric oxide contributes to protection from tuberculosis. It is generally assumed that this
protection is due to direct inhibition of Mycobacterium tuberculosis growth, which prevents …

Tuberculosis is the leading cause of death by an infectious disease worldwide. However, the
involvement of innate lymphoid cells (ILCs) in immune responses to infection with …

ABSTRACT Mycobacterium bovis Bacille Calmette-Guérin (BCG) is the only licensed
vaccine against tuberculosis (TB), yet its moderate efficacy against pulmonary TB calls for …

Pulmonary cavities, the hallmark of tuberculosis (TB), are characterized by high
mycobacterial load and perpetuate the spread of M. tuberculosis. The mechanism of matrix …