Oxidative stress in asthma and COPD: antioxidants as a therapeutic strategy

P Kirkham, I Rahman - Pharmacology & therapeutics, 2006 - Elsevier
Asthma and chronic obstructive pulmonary disease (COPD) are inflammatory lung diseases
that are characterized by systemic and chronic localized inflammation and oxidative stress …

Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: an emerging need for novel drug delivery systems

K Dua, V Malyla, G Singhvi, R Wadhwa… - Chemico-biological …, 2019 - Elsevier
Oxidative stress is intensely involved in enhancing the severity of various chronic respiratory
diseases (CRDs) including asthma, chronic obstructive pulmonary disease (COPD) …

The role of oxidative stress in the pathogenesis of asthma

YS Cho, HB Moon - Allergy, asthma & immunology research, 2010 - synapse.koreamed.org
Oxidative stress plays a critical role in the pathogenesis of asthma. To effectively control
oxidative stress in asthmatics, it is important to investigate the precise intracellular …

Oxidant—antioxidant imbalance in asthma: scientific evidence, epidemiological data and possible therapeutic options

A Nadeem, A Masood… - Therapeutic advances in …, 2008 - journals.sagepub.com
Prevalence of asthma has increased considerably in recent decades throughout the world
especially in developed countries. Airway inflammation is thought to be prime cause for …

Glutathione peroxidase enzyme activity in aging

SE Espinoza, H Guo, N Fedarko… - The Journals of …, 2008 - academic.oup.com
Background. It is hypothesized that free radical damage contributes to aging. Age-related
decline in activity of the antioxidant enzyme glutathione peroxidase (GPx) may contribute to …

Obesity, asthma, and oxidative stress

F Holguin, A Fitzpatrick - Journal of Applied Physiology, 2010 - journals.physiology.org
Obesity is associated with increased systemic and airway oxidative stress, which may result
from a combination of adipokine imbalance, comorbidities, and reduced antioxidant …

Airway and systemic oxidant-antioxidant dysregulation in asthma: a possible scenario of oxidants spill over from lung into blood

A Nadeem, N Siddiqui, NO Alharbi… - Pulmonary pharmacology …, 2014 - Elsevier
Asthma is characterized by repeated episodes of airway obstruction and an ongoing cycle of
airway inflammation. Reactive oxygen species (ROS) produced by inflammatory cells in the …

Oxidative stress and macrophages: driving forces behind exacerbations of asthma and chronic obstructive pulmonary disease?

LES de Groot, TA Van Der Veen… - … of physiology-lung …, 2019 - journals.physiology.org
Oxidative stress is a common feature of obstructive airway diseases like asthma and chronic
obstructive pulmonary disease (COPD). Lung macrophages are key innate immune cells …

[HTML][HTML] The effect of hydro-ethanolic extract of Curcuma longa rhizome and curcumin on total and differential WBC and serum oxidant, antioxidant biomarkers in rat …

F Shakeri, M Soukhtanloo… - Iranian journal of basic …, 2017 - ncbi.nlm.nih.gov
Objective (s): The effects of Curcuma longa (C. longa) and curcumin on total and differential
WBC count and oxidant, antioxidant biomarkers, in rat model of asthma were evaluated …

The alleviating impacts of quercetin on inflammation and oxidant-antioxidant imbalance in rats with allergic asthma

MA Rajizadeh, MA Bejeshk… - Iranian Journal of …, 2023 - ijaai.tums.ac.ir
The Alleviating Impacts of Quercetin on Inflammation and Oxidant- antioxidant Imbalance in
Rats with Allergic Asthma Page 1 Copyright © 2023 Rajizadeh et al. Published by Tehran …