Multi-omics experiments at bulk or single-cell resolution facilitate the discovery of hypothesis-
generating biomarkers for predicting response to therapy, as well as aid in uncovering …

Motivation Asthma is a heterogeneous disease where various subtypes are established and
molecular biomarkers of the subtypes are yet to be discovered. Recent availability of multi …

Survival prediction models play a key role in patient prognosis and personalized treatment.
However, their accuracy can be improved by incorporating patient similarity networks, which …

Elucidating the molecular dependencies behind the cancer-type specificity of driver
mutations may reveal new therapeutic opportunities. We hypothesized that developmental …

The increasing availability of high-dimensional, longitudinal measures of gene expression
can facilitate understanding of biological mechanisms, as required for precision medicine …

The development of sequencing technology has promoted the expansion of cancer genome
data. It is necessary to identify the pathogenesis of cancer at the molecular level and explore …

The subtypes of breast cancer exhibit diverse histology, molecular features, therapeutic
response, aggressiveness, and patient outcomes. Multi-omics high-throughput technologies …