Genome-wide analysis of human long noncoding RNAs: a provocative review

CP Ponting, W Haerty - Annual review of genomics and human …, 2022 - annualreviews.org
Do long noncoding RNAs (lncRNAs) contribute little or substantively to human biology? To
address how lncRNA loci and their transcripts, structures, interactions, and functions …

The how and why of lncRNA function: an innate immune perspective

EK Robinson, S Covarrubias, S Carpenter - Biochimica et Biophysica Acta …, 2020 - Elsevier
Next-generation sequencing has provided a more complete picture of the composition of the
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …

Predicting the potential human lncRNA–miRNA interactions based on graph convolution network with conditional random field

W Wang, L Zhang, J Sun, Q Zhao… - Briefings in …, 2022 - academic.oup.com
Long non-coding RNA (lncRNA) and microRNA (miRNA) are two typical types of non-coding
RNAs (ncRNAs), their interaction plays an important regulatory role in many biological …

Using network distance analysis to predict lncRNA–miRNA interactions

L Zhang, P Yang, H Feng, Q Zhao, H Liu - … sciences: computational life …, 2021 - Springer
LncRNA–miRNA interactions contribute to the regulation of therapeutic targets and
diagnostic biomarkers in multifarious human diseases. However, it remains difficult to …

The functions and unique features of LncRNAs in cancer development and tumorigenesis

K Taniue, N Akimitsu - International journal of molecular sciences, 2021 - mdpi.com
Over the past decades, research on cancer biology has focused on the involvement of
protein-coding genes in cancer development. Long noncoding RNAs (lncRNAs), which are …

LncRNA2Target v2. 0: a comprehensive database for target genes of lncRNAs in human and mouse

L Cheng, P Wang, R Tian, S Wang, Q Guo… - Nucleic acids …, 2019 - academic.oup.com
Long non-coding RNAs (lncRNAs) play crucial roles in regulating gene expression, and a
growing number of researchers have focused on the identification of target genes of …

LncBook: a curated knowledgebase of human long non-coding RNAs

L Ma, J Cao, L Liu, Q Du, Z Li, D Zou… - Nucleic acids …, 2019 - academic.oup.com
Long non-coding RNAs (lncRNAs) have significant functions in a wide range of important
biological processes. Although the number of known human lncRNAs has dramatically …

Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion

L Huang, L Zhang, X Chen - Briefings in bioinformatics, 2022 - academic.oup.com
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

LncSEA: a platform for long non-coding RNA related sets and enrichment analysis

J Chen, J Zhang, Y Gao, Y Li, C Feng… - Nucleic acids …, 2021 - academic.oup.com
Long non-coding RNAs (lncRNAs) have been proven to play important roles in
transcriptional processes and various biological functions. Establishing a comprehensive …

lncRNASNP v3: an updated database for functional variants in long non-coding RNAs

Y Yang, D Wang, YR Miao, X Wu, H Luo… - Nucleic Acids …, 2023 - academic.oup.com
Long non-coding RNAs (lncRNAs) act as versatile regulators of many biological processes
and play vital roles in various diseases. lncRNASNP is dedicated to providing a …