Continuing discoveries of new and surprising mechanisms of gene regulation suggest that
our understanding of this complex and ubiquitous biological process remains incomplete …

Post-transcriptional control makes a major contribution to the overall regulation of gene
expression pathway. Within the cytoplasm this is mediated by a combination of regulatory …

Control of gene expression is achieved at various levels. Translational control becomes
crucial in the absence of transcription, such as occurs in early developmental stages. One of …

There is now a growing body of evidence which suggests links between the regulation of
protein synthesis and the disruption of cell behaviour that typifies cancer. This directed issue …

Studies of bacterial and eukaryotic systems have identified two-gene operons in which the
translation product of the upstream gene influences translation of the downstream gene. The …

TOP mRNAs are vertebrate transcripts which contain a 5′ terminal oligopyrimidine tract
(5′ TOP), encode for ribosomal proteins and elongation factors 1α and 2, and are …

A molecular approach has been used to study the role of polyamines in plant development
by manipulating the expression of the S‐adenosylmethionine decarboxylase (SAMDC) …

Synthesis of S-adenosylmethionine decarboxylase (AdoMetDC), a key regulated enzyme in
the pathway of polyamine biosynthesis, is feedback-controlled at the level of translation by …

A novel form of translational regulation is described for the key polyamine biosynthetic
enzyme S-adenosylmethionine decarboxylase (AdoMetDC). Plant AdoMetDC mRNA 5 …

The mRNAs for two key enzymes in polyamine biosynthesis, ornithine decarboxlase (ODC)
and S-adenosylmethionine decarboxylase (AdoMetDC), both have long 5′ untranslated …