Cardiovascular disease in chronic kidney disease: pathophysiological insights and therapeutic options
J Jankowski, J Floege, D Fliser, M Böhm, N Marx - Circulation, 2021 - Am Heart Assoc
Patients with chronic kidney disease (CKD) exhibit an elevated cardiovascular risk
manifesting as coronary artery disease, heart failure, arrhythmias, and sudden cardiac …
manifesting as coronary artery disease, heart failure, arrhythmias, and sudden cardiac …
Medial Arterial Calcification: JACC State-of-the-Art Review
Medial arterial calcification (MAC) is a chronic systemic vascular disorder distinct from
atherosclerosis that is frequently but not always associated with diabetes mellitus, chronic …
atherosclerosis that is frequently but not always associated with diabetes mellitus, chronic …
Targeting vascular calcification in chronic kidney disease
Cardiovascular (CV) disease remains an important cause of morbidity and mortality for
patients with chronic kidney disease (CKD). Although clustering of traditional risk factors with …
patients with chronic kidney disease (CKD). Although clustering of traditional risk factors with …
Cardiovascular calcification heterogeneity in chronic kidney disease
JD Hutcheson, C Goettsch - Circulation Research, 2023 - Am Heart Assoc
Patients with chronic kidney disease (CKD) exhibit tremendously elevated risk for
cardiovascular disease, particularly ischemic heart disease, due to premature vascular and …
cardiovascular disease, particularly ischemic heart disease, due to premature vascular and …
Multicenter randomized controlled trial of vitamin K antagonist replacement by rivaroxaban with or without vitamin K2 in hemodialysis patients with atrial fibrillation: the …
AS De Vriese, R Caluwé, L Pyfferoen… - Journal of the …, 2020 - journals.lww.com
Background Vitamin K antagonists (VKAs), although commonly used to reduce
thromboembolic risk in atrial fibrillation, have been incriminated as probable cause of …
thromboembolic risk in atrial fibrillation, have been incriminated as probable cause of …
Metformin prevents methylglyoxal-induced apoptosis by suppressing oxidative stress in vitro and in vivo
G Wang, Y Wang, Q Yang, C Xu, Y Zheng… - Cell Death & …, 2022 - nature.com
Methylglyoxal (MGO) is an active metabolite of glucose and plays a prominent role in the
pathogenesis of diabetic vascular complications, including endothelial cell apoptosis …
pathogenesis of diabetic vascular complications, including endothelial cell apoptosis …
Uraemic solutes as therapeutic targets in CKD-associated cardiovascular disease
JD Ravid, MH Kamel, VC Chitalia - Nature Reviews Nephrology, 2021 - nature.com
Chronic kidney disease (CKD) is characterized by the retention of a myriad of solutes termed
uraemic (or uremic) toxins, which inflict damage to several organs, including the …
uraemic (or uremic) toxins, which inflict damage to several organs, including the …
Interventions to attenuate vascular calcification progression in chronic kidney disease: a systematic review of clinical trials
C Xu, ER Smith, MK Tiong, I Ruderman… - Journal of the …, 2022 - journals.lww.com
Interventions To Attenuate Vascular Calcification Progressio... : Journal of the American
Society of Nephrology Interventions To Attenuate Vascular Calcification Progression in Chronic …
Society of Nephrology Interventions To Attenuate Vascular Calcification Progression in Chronic …
[HTML][HTML] Strategies for phosphate control in patients with CKD
FC Barreto, DV Barreto, ZA Massy… - Kidney international reports, 2019 - Elsevier
Hyperphosphatemia is a common complication in patients with chronic kidney disease
(CKD), particularly in those requiring renal replacement therapy. The importance of …
(CKD), particularly in those requiring renal replacement therapy. The importance of …
[HTML][HTML] Hyperphosphatemia and cardiovascular disease
C Zhou, Z Shi, N Ouyang, X Ruan - Frontiers in Cell and …, 2021 - frontiersin.org
Hyperphosphatemia or even serum phosphate levels within the “normal laboratory range”
are highly associated with increased cardiovascular disease risk and mortality in the general …
are highly associated with increased cardiovascular disease risk and mortality in the general …