Lipopolysaccharide (LPS) is a crucial constituent of the outer membrane of most Gram-
negative bacteria, playing a fundamental role in the protection of bacteria from …

The C-type lectins are a superfamily of proteins that recognize a broad repertoire of ligands
and that regulate a diverse range of physiological functions. Most research attention has …

The progression of pancreatic oncogenesis requires immune-suppressive inflammation in
cooperation with oncogenic mutations. However, the drivers of intratumoral immune …

Abstract Colony-stimulating factor-1 receptor (CSF-1R), also known as FMS kinase, is a type
I single transmembrane protein mainly expressed in myeloid cells, such as monocytes …

Over the last decade, C-type lectin-like receptors (CTLRs), expressed mostly by myeloid
cells, have gained increasing attention for their role in the fine tuning of both innate and …

Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an
emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin …

Abstract Dectin-1 (gene Clec7a), a receptor for β-glucans, plays important roles in the host
defense against fungi and immune homeostasis of the intestine. Although this molecule is …

The gut-liver axis covers the bidirectional communication between the gut and the liver, and
thus includes signals from liver-to-gut (eg, bile acids, immunoglobulins) and from gut-to-liver …

Myeloid C-type lectin receptors (CLRs) are important sensors of self and non-self that work
in concert with other pattern recognition receptors (PRRs). CLRs have been previously …

Nonalcoholic fatty liver disease prevalence is soaring with the obesity pandemic, but the
pathogenic mechanisms leading to the progression toward active nonalcoholic …