Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation
CW Shields Iv, CD Reyes, GP López - Lab on a Chip, 2015 - pubs.rsc.org
Accurate and high throughput cell sorting is a critical enabling technology in molecular and
cellular biology, biotechnology, and medicine. While conventional methods can provide high …
cellular biology, biotechnology, and medicine. While conventional methods can provide high …
Inertial microfluidic physics
Microfluidics has experienced massive growth in the past two decades, and especially with
advances in rapid prototyping researchers have explored a multitude of channel structures …
advances in rapid prototyping researchers have explored a multitude of channel structures …
Particle separation and sorting in microfluidic devices: a review
Separation and sorting of micron-sized particles has great importance in diagnostics,
chemical and biological analyses, food and chemical processing and environmental …
chemical and biological analyses, food and chemical processing and environmental …
Inertial focusing in microfluidics
When Segré and Silberberg in 1961 witnessed particles in a laminar pipe flow congregating
at an annulus in the pipe, scientists were perplexed and spent decades learning why such …
at an annulus in the pipe, scientists were perplexed and spent decades learning why such …
Isolation and retrieval of circulating tumor cells using centrifugal forces
Presence and frequency of rare circulating tumor cells (CTCs) in bloodstreams of cancer
patients are pivotal to early cancer detection and treatment monitoring. Here, we use a spiral …
patients are pivotal to early cancer detection and treatment monitoring. Here, we use a spiral …
Inertial microfluidics
D Di Carlo - Lab on a Chip, 2009 - pubs.rsc.org
Despite the common wisdom that inertia does not contribute to microfluidic phenomena,
recent work has shown a variety of useful effects that depend on fluid inertia for applications …
recent work has shown a variety of useful effects that depend on fluid inertia for applications …
Nonlinear microfluidics
D Stoecklein, D Di Carlo - Analytical chemistry, 2018 - ACS Publications
Microfluidic flow is commonly employed in the biological, chemical, or physical analysis of
samples in small fluid volumes because of the typical lack of nonlinear phenomena, with …
samples in small fluid volumes because of the typical lack of nonlinear phenomena, with …
Continuous separation of cells and particles in microfluidic systems
A Lenshof, T Laurell - Chemical Society Reviews, 2010 - pubs.rsc.org
The progress in microfabrication and lab-on-a-chip technologies has been a major area of
development for new approaches to bioanalytics and integrated concepts for cell biology …
development for new approaches to bioanalytics and integrated concepts for cell biology …
Spiral microchannel with rectangular and trapezoidal cross-sections for size based particle separation
The paper reports a new method for three-dimensional observation of the location of
focused particle streams along both the depth and width of the channel cross-section in …
focused particle streams along both the depth and width of the channel cross-section in …
High-yield cell ordering and deterministic cell-in-droplet encapsulation using Dean flow in a curved microchannel
EWM Kemna, RM Schoeman, F Wolbers, I Vermes… - Lab on a Chip, 2012 - pubs.rsc.org
In this article high-yield (77%) and high-speed (2700 cells s− 1) single cell droplet
encapsulation is described using a Dean-coupled inertial ordering of cells in a simple …
encapsulation is described using a Dean-coupled inertial ordering of cells in a simple …