Triggering receptors expressed on myeloid cells (TREMs) encompass a family of cell-
surface receptors chiefly expressed by granulocytes, monocytes and tissue macrophages …

Psoriasis vulgaris is the best-understood autoimmune skin disease mediated by the cells
and molecules of the innate and adaptive immune systems. In many ways, the immune …

Triggering receptor expressed on myeloid cells-1 (TREM-1) is expressed on the majority of
innate immune cells and to a lesser extent on parenchymal cells. Upon activation, TREM-1 …

Background Genomic profiling of lesional and nonlesional skin of patients with atopic
dermatitis (AD) using microarrays has led to increased understanding of AD and …

Psoriasis vulgaris, affecting the skin, is one of the most common organ-specific autoimmune
diseases in humans. Until recently, psoriasis was treated by agents or approaches …

Diabetic foot ulcers (DFU) are a serious complication of diabetes mellitus and associated
with reduced quality of life and high mortality rate. DFUs are characterized by a deregulated …

During the last decades, high-throughput assessment of gene expression in patient tissues
using microarray technology or RNA-Seq took center stage in clinical research. Insights into …

By participating in both the recruitment and activation of T lymphocytes, macrophages and
neutrophils at the site of psoriatic inflammation, chemokines play an important role in the …

Psoriasis is a common chronic, immune‑mediated, inflammatory skin disorder, with a
reported prevalence of 0.0‑2.1% among children and 0.91‑8.50% among adults, worldwide …

Triggering receptor expressed on myeloid cells-1 (TREM-1) is a potent amplifier of pro-
inflammatory innate immune responses, but its significance in non-infectious diseases …