Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

Understanding the pathogenesis of an infectious disease is critical for developing new
methods to prevent infection and diagnose or cure disease. Adherence of microorganisms to …

Laminin (Ln) and collagen are multifunctional glycoproteins that play an important role in
cellular morphogenesis, cell signalling, tissue repair and cell migration. These proteins are …

While most Ascomycetes tend to associate principally with plants, the dimorphic fungi
Coccidioides immitis and Coccidioides posadasii are primary pathogens of …

The recognition of fungal cells by the host immune system is key during the establishment of
a protective anti-fungal response. Even though the immune system has evolved a vast …

Background The asexual fungus Fusarium oxysporum f. sp. cubense (Foc) causing vascular
wilt disease is one of the most devastating pathogens of banana (Musa spp.). To understand …

The signature feature of systemic dimorphic fungi–a family of six primary fungal pathogens
of humans–is a temperature-induced phase transition. These fungi grow as a mold in soil at …

Coccidioides immitis and C. posadasii are two highly pathogenic dimorphic fungal species
that are endemic in the arid areas of the new world, including the region from west Texas to …

Abstract The genera Trichophyton, Microsporum, and Epidermophyton include filamentous
fungi that cause dermatophytosis, a superficial infection of the skin, stratum corneum, nail …

Dermatophytes are a highly specialized group of keratinophilic and keratinolytic filamentous
fungi causing a ringworm disease called dermatophytosis or superficial mycoses. Although …