miRNA biogenesis and regulation of diseases: an updated overview

A Vishnoi, S Rani - MicroRNA Profiling: Methods and Protocols, 2022 - Springer
MicroRNAs (miRNAs) are small RNA molecules, with their role in gene silencing and
translational repression by binding to the target mRNAs. Since it was discovered in 1993 …

Exosomes as bio-inspired nanocarriers for RNA delivery: preparation and applications

A Amiri, R Bagherifar, E Ansari Dezfouli… - Journal of Translational …, 2022 - Springer
Nanocarriers as drug/biomolecule delivery systems have been significantly developed
during recent decades. Given the stability, reasonable delivery efficiency, and safety of …

Recent advances in miRNA delivery systems

I Dasgupta, A Chatterjee - Methods and protocols, 2021 - mdpi.com
MicroRNAs (miRNAs) represent a family of short non-coding regulatory RNA molecules that
are produced in a tissue and time-specific manner to orchestrate gene expression post …

Extracellular vesicle miRNAs promote the intestinal microenvironment by interacting with microbes in colitis

Q Shen, Z Huang, L Ma, J Yao, T Luo, Y Zhao… - Gut …, 2022 - Taylor & Francis
Inflammatory bowel disease (IBD) is a global disease with no cure. Disruption of the
microbial ecosystem is considered to be an important cause of IBD. Extracellular vesicles …

[HTML][HTML] Mesenchymal stem cell-derived exosomal microRNA-367–3p alleviates experimental autoimmune encephalomyelitis via inhibition of microglial ferroptosis by …

J Fan, Y Han, H Sun, S Sun, Y Wang, R Guo… - Biomedicine & …, 2023 - Elsevier
Multiple sclerosis (MS) is an autoimmune, inflammatory demyelinating disorder of the central
nervous system. Accumulating evidence has underscored the therapeutic potential of bone …

State of the art: the immunomodulatory role of MSCs for osteoarthritis

DG Kwon, MK Kim, YS Jeon, YC Nam, JS Park… - International journal of …, 2022 - mdpi.com
Osteoarthritis (OA) has generally been introduced as a degenerative disease; however, it
has recently been understood as a low-grade chronic inflammatory process that could …

Mesenchymal stem cell-derived exosomes and MicroRNAs in cartilage regeneration: biogenesis, efficacy, miRNA enrichment and delivery

JB Foo, QH Looi, CW How, SH Lee, ME Al-Masawa… - Pharmaceuticals, 2021 - mdpi.com
Exosomes are the small extracellular vesicles secreted by cells for intercellular
communication. Exosomes are rich in therapeutic cargos such as microRNA (miRNA), long …

Advances in development of exosomes for ophthalmic therapeutics

Y Tian, T Zhang, J Li, Y Tao - Advanced Drug Delivery Reviews, 2023 - Elsevier
Exosomes contain multiple bioactive molecules and maintain the connection between cells.
Recent advances in exosome-based therapeutics have witnessed unprecedented …

Evaluating the influence of Human Umbilical Cord Mesenchymal Stem Cells-derived exosomes loaded with miR-3182 on metastatic performance of Triple Negative …

Y Khazaei-Poul, S Shojaei, A Koochaki, H Ghanbarian… - Life sciences, 2021 - Elsevier
Abstract Aims Deregulation of microRNA (miRNA) function has been linked to numerous
human cancers, such as Triple Negative Breast Cancer (TNBC). Exosomes, a subgroup of …

Circulating miRNAs in breast cancer diagnosis and prognosis

B Cardinali, R Tasso, P Piccioli, MC Ciferri, R Quarto… - Cancers, 2022 - mdpi.com
Simple Summary In the era of precision medicine, new tools for better management of breast
cancer patients are still needed. From this perspective, circulating microRNA (miRNA), a …