Regenerative medicine, the most recent and emerging branch of medical science, deals
with functional restoration of tissues or organs for the patient suffering from severe injuries or …

Neurologic impairments are usually irreversible as a result of limited regeneration in the
central nervous system. Therefore, based on the regenerative capacity of stem cells …

Reliable genome editing via Clustered Regularly Interspaced Short Palindromic Repeat
(CRISPR)/Cas9 may provide a means to correct inherited diseases in patients. As proof of …

The human retina fails to regenerate and cell-based therapies offer options for treatment of
blinding retinal diseases, such as macular degeneration and retinitis pigmentosa. The last …

Stem cell-derived retinal pigment epithelium (RPE) and photoreceptors (PRs) have restored
vision in preclinical models of human retinal degenerative disease. This review discusses …

Premature ovarian failure (POF) usually happens former to the age of 40 and affects the
female physiological state premenopausal period. In this condition, ovaries stop working …

Cell-based therapeutics offer diverse options for treating retinal degenerative diseases, such
as age-related macular degeneration (AMD) and retinitis pigmentosa (RP). AMD is …

Mitofusin-2 (MFN2) is a mitochondrial outer-membrane protein that plays a pivotal role in
mitochondrial dynamics in most tissues, yet mutations in MFN2, which cause Charcot-Marie …

Traumatic brain injury (TBI) in humans can result in permanent tissue damage and has been
linked to cognitive impairment that lasts years beyond the initial insult. Clinically effective …

Human induced pluripotent stem cells (iPSCs) are a renewable cell source that can be
differentiated into neural progenitor cells (iNPCs) and transduced with glial cell line-derived …