Synthetic systems powered by biological molecular motors
Biological molecular motors (or biomolecular motors for short) are nature's solution to the
efficient conversion of chemical energy to mechanical movement. In biological systems …
efficient conversion of chemical energy to mechanical movement. In biological systems …
Non-equilibrium assembly of microtubules: from molecules to autonomous chemical robots
Biological systems have evolved to harness non-equilibrium processes from the molecular
to the macro scale. It is currently a grand challenge of chemistry, materials science, and …
to the macro scale. It is currently a grand challenge of chemistry, materials science, and …
An overview of sub-cellular mechanisms involved in the action of TTFields
JA Tuszynski, C Wenger, DE Friesen… - International journal of …, 2016 - mdpi.com
Long-standing research on electric and electromagnetic field interactions with biological
cells and their subcellular structures has mainly focused on the low-and high-frequency …
cells and their subcellular structures has mainly focused on the low-and high-frequency …
All wired up: an exploration of the electrical properties of microtubules and tubulin
Microtubules are hollow, cylindrical polymers of the protein α, β tubulin, that interact
mechanochemically with a variety of macromolecules. Due to their mechanically robust …
mechanochemically with a variety of macromolecules. Due to their mechanically robust …
Modulation of microtubule properties and functions by encapsulation of nanomaterials using a Tau-derived peptide
H Inaba, K Matsuura - Bulletin of the Chemical Society of Japan, 2021 - academic.oup.com
Microtubules (MTs) are hollow cytoskeletons with typically 15 nm inner diameter, which are
crucial for various cellular activities including structural support, transport, and cell division …
crucial for various cellular activities including structural support, transport, and cell division …
Modeling microtubule counterion distributions and conductivity using the Poisson-Boltzmann equation
Microtubules are highly negatively charged proteins which have been shown to behave as
bio-nanowires capable of conducting ionic currents. The electrical characteristics of …
bio-nanowires capable of conducting ionic currents. The electrical characteristics of …
Tubulin's response to external electric fields by molecular dynamics simulations
Tubulin heterodimers are the building blocks of microtubules and disruption of their
dynamics is exploited in the treatment of cancer. Electric fields at certain frequencies and …
dynamics is exploited in the treatment of cancer. Electric fields at certain frequencies and …
Investigation of the electrical properties of microtubule ensembles under cell-like conditions
Microtubules are hollow cylindrical polymers composed of the highly negatively-charged (~
23e), high dipole moment (1750 D) protein α, β-tubulin. While the roles of microtubules in …
23e), high dipole moment (1750 D) protein α, β-tubulin. While the roles of microtubules in …
Control of molecular shuttles by designing electrical and mechanical properties of microtubules
Kinesin-driven microtubules have been focused on to serve as molecular transporters,
called “molecular shuttles,” to replace micro/nanoscale molecular manipulations …
called “molecular shuttles,” to replace micro/nanoscale molecular manipulations …
Blocking exposed PD-L1 elicited by nanosecond pulsed electric field reverses dysfunction of CD8+ T cells in liver cancer
J Qian, T Chen, Q Wu, L Zhou, W Zhou, L Wu, S Wang… - Cancer Letters, 2020 - Elsevier
As a promising method for local tumor treatment, nanosecond pulsed electric field (nsPEF)
ablation elicits a potent anti-tumor immune response. However, the mechanism of the nsPEF …
ablation elicits a potent anti-tumor immune response. However, the mechanism of the nsPEF …