No broadly effective vaccines are available for prevention of group B meningococcal
disease, which accounts for> 50% of all cases. The group B capsule is an autoantigen and …

The diversity and dynamics of Neisseria meningitidis populations generate a requirement for
high resolution, comprehensive, and portable typing schemes for meningococcal disease …

Genome-Wide Association Studies (GWAS) in microbial organisms have the potential to
vastly improve the way we understand, manage, and treat infectious diseases. Yet, microbial …

Background Multi-locus sequence typing (MLST) is a method of typing that facilitates the
discrimination of microbial isolates by comparing the sequences of housekeeping gene …

Background Highly parallel,'second generation'sequencing technologies have rapidly
expanded the number of bacterial whole genome sequences available for study, permitting …

Neisseria meningitidis is an important cause of septicemia and meningitis. To cause
disease, the bacterium must successfully survive in the bloodstream where it has to avoid …

The bacterium Neisseria meningitidis is a major cause of meningitis and septicemia
worldwide. Outer membrane proteins (OMPs) are candidates in the search for …

Background Neisseria meningitidis serogroup C (NmC) outbreaks occur infrequently in the
African meningitis belt; the most recent report of an outbreak of this serogroup was in …

Neisseria meningitis is a human commensal bacterium that occasionally causes life-
threatening disease. As with a number of other bacterial pathogens, meningococcal …

Neisseria meningitidis is a leading bacterial cause of sepsis and meningitis globally with
dynamic strain distribution over time. Beginning with an epidemic among Hajj pilgrims in …