Introduction: Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases
capable of degrading extracellular matrix, including the basement membrane. MMPs are …

Matrix metalloproteinases (MMPs) play an important role in tissue remodelling associated
with various physiological and pathological processes, such as morphogenesis …

Despite significant advances in treating heart disease, heart failure remains a major cause
of morbidity and mortality. Regardless of the initiating cause (s), heart failure is associated …

Matrix metalloproteinases (MMPs, matrixins) are a family of secreted and membrane-bound
zinc-dependent endopeptidases that have the combined capacity to degrade all the …

Matrix metalloproteinase (MMPs) are long understood to be involved in remodeling of the
extracellular matrix. However, over the past decade, it has become clear that one of the most …

Since their inaugural discovery in the early 1960s, matrix metalloproteinases (MMPs) have
been shown to mediate multiple physiological and pathological processes. In addition to …

Objective Turnover of the extracellular matrix in all solid organs is governed mainly by a
balance between the degrading matrix metalloproteinases (MMPs) and their tissue inhibitors …

Background We hypothesized that adipose-derived mesenchymal stem cells (ADMSCs)
may ameliorate sepsis-induced acute lung injury (ALI) and change microorganism …

Basic pharmacological/transgenic studies have clearly demonstrated a cause–effect
relationship between the induction and activation of matrix metalloproteinases (MMPs) and …

Uncontrolled regulation of specific metalloenzymes plays important roles in several
diseases like tumor metastasis and inflammation. Therefore, selective metalloenzyme …