[HTML][HTML] The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease
E Mogilyansky, I Rigoutsos - Cell Death & Differentiation, 2013 - nature.com
Abstract The miR-17/92 cluster is among the best-studied microRNA clusters. Interest in the
cluster and its members has been increasing steadily and the number of publications has …
cluster and its members has been increasing steadily and the number of publications has …
MicroRNA-125 in immunity and cancer
JK Wang, Z Wang, G Li - Cancer letters, 2019 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that play a wide variety of critical roles in
different biological processes by post-transcriptionally regulating gene expression. They …
different biological processes by post-transcriptionally regulating gene expression. They …
MicroRNA-124 regulates STAT3 expression and is down-regulated in colon tissues of pediatric patients with ulcerative colitis
G Koukos, C Polytarchou, JL Kaplan… - Gastroenterology, 2013 - Elsevier
Background & Aims Altered levels and functions of microRNAs (miRs) have been associated
with inflammatory bowel diseases (IBDs), although little is known about their roles in …
with inflammatory bowel diseases (IBDs), although little is known about their roles in …
[HTML][HTML] STATs: an old story, yet mesmerizing
Signal transducers and activators of transcription (STATs) are cytoplasmic transcription
factors that have a key role in cell fate. STATs, a protein family comprised of seven members …
factors that have a key role in cell fate. STATs, a protein family comprised of seven members …
MicroRNA-125b promotes apoptosis by regulating the expression of Mcl-1, Bcl-w and IL-6R
J Gong, JP Zhang, B Li, C Zeng, K You, MX Chen… - Oncogene, 2013 - nature.com
The microRNA miR-125b is multi-faceted, with the ability to function as a tumor suppressor
or an oncogene, depending on the cellular context. To date, the pro-apoptotic role of miR …
or an oncogene, depending on the cellular context. To date, the pro-apoptotic role of miR …
miR-99a/100∼ 125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFβ and Wnt signaling
S Emmrich, M Rasche, J Schöning… - Genes & …, 2014 - genesdev.cshlp.org
Although regulation of stem cell homeostasis by microRNAs (miRNAs) is well studied, it is
unclear how individual miRNAs genomically encoded within an organized polycistron can …
unclear how individual miRNAs genomically encoded within an organized polycistron can …
MiR-125 in normal and malignant hematopoiesis
L Shaham, V Binder, N Gefen, A Borkhardt, S Izraeli - Leukemia, 2012 - nature.com
MiR-125 is a highly conserved microRNA throughout many different species from nematode
to humans. In humans, there are three homologs (hsa-miR-125b-1, hsa-miR-125b-2 and …
to humans. In humans, there are three homologs (hsa-miR-125b-1, hsa-miR-125b-2 and …
[HTML][HTML] Dysregulated microRNAs in amyotrophic lateral sclerosis microglia modulate genes linked to neuroinflammation
C Parisi, I Arisi, N D'Ambrosi, AE Storti, R Brandi… - Cell death & …, 2013 - nature.com
MicroRNAs (miRNAs) regulate gene expression at post-transcriptional level and are key
modulators of immune system, whose dysfunction contributes to the progression of …
modulators of immune system, whose dysfunction contributes to the progression of …
[HTML][HTML] MicroRNAs are shaping the hematopoietic landscape
Hematopoiesis is regulated by microRNAs (miRNAs). These small regulatory RNAs are
master regulators of developmental processes that modulate expression of several target …
master regulators of developmental processes that modulate expression of several target …
miRNA regulation of innate immunity
F Momen-Heravi, S Bala - Journal of leukocyte biology, 2018 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNA and are pivotal posttranscriptional
regulators of both innate and adaptive immunity. They act by regulating the expression of …
regulators of both innate and adaptive immunity. They act by regulating the expression of …