Cationic liposomes (CLs) are effective carriers of a variety of therapeutics. Their applications
as vectors of nucleic acids (NAs), from long DNA and mRNA to short interfering RNA …

Chain-like macromolecules (polymers) show characteristic adsorption properties due to their
flexibility and internal degrees of freedom, when attracted to surfaces and interfaces. In this …

Polysarcosine (pSar) is a polypeptoid based on the endogenous amino acid sarcosine (N-
methylated glycine), which has previously shown potent stealth properties. Here, lipid …

A two-dimensional columnar phase in mixtures of DNA complexed with cationic liposomes
has been found in the lipid composition regime known to be significantly more efficient at …

An overview of recent experimental and theoretical developments in the field of the physics
of membranes, including new insights from the past decade. The author uses classical …

▪ Abstract Owing to the rapid development of in vivo applications for non-viral gene delivery
vectors, it is necessary to have a better understanding of how the structure-activity …

Recently, there has been a flurry of experimental work on understanding the supramolecular
assemblies that are formed when cationic liposomes (CLs) are mixed with DNA. From a …

Langmuir monolayers at the liquid–air interface are well-defined interfacial systems and,
therefore, excellent model systems to learn about interactions at interfaces beyond the …

Abstract Cationic lipid–DNA (CL-DNA) complexes comprise a promising new class of
synthetic nonviral gene delivery systems. When positively charged, they attach to the anionic …

We study theoretically the adsorption of semiflexible charged polymers on an oppositely
charged flat substrate. We restrict ourselves to polymers with relatively high line charge …