Engineered human blood–brain barrier microfluidic model for vascular permeability analyses
The blood–brain barrier (BBB) greatly restricts the entry of biological and engineered
therapeutic molecules into the brain. Due to challenges in translating results from animal …
therapeutic molecules into the brain. Due to challenges in translating results from animal …
Hydrogels as drug delivery systems: A review of current characterization and evaluation techniques
Owing to their tunable properties, controllable degradation, and ability to protect labile
drugs, hydrogels are increasingly investigated as local drug delivery systems. However, a …
drugs, hydrogels are increasingly investigated as local drug delivery systems. However, a …
Conventional and emerging strategies for the fabrication and functionalization of PDMS-based microfluidic devices
Microfluidics is an emerging and multidisciplinary field that is of great interest to
manufacturers in medicine, biotechnology, and chemistry, as it provides unique tools for the …
manufacturers in medicine, biotechnology, and chemistry, as it provides unique tools for the …
Advances in organ-on-a-chip engineering
Predicting the effects of drugs before human clinical trials is at the heart of drug screening
and discovery processes. The cost of drug discovery is steadily increasing owing to the …
and discovery processes. The cost of drug discovery is steadily increasing owing to the …
Microfluidic chips: recent advances, critical strategies in design, applications and future perspectives
Microfluidic chip technology is an emerging tool in the field of biomedical application.
Microfluidic chip includes a set of groves or microchannels that are engraved on different …
Microfluidic chip includes a set of groves or microchannels that are engraved on different …
A bioprinted human-glioblastoma-on-a-chip for the identification of patient-specific responses to chemoradiotherapy
Patient-specific ex vivo models of human tumours that recapitulate the pathological
characteristics and complex ecology of native tumours could help determine the most …
characteristics and complex ecology of native tumours could help determine the most …
Strategies for 3D bioprinting of spheroids: A comprehensive review
Biofabricated tissues have found numerous applications in tissue engineering and
regenerative medicine in addition to the promotion of disease modeling and drug …
regenerative medicine in addition to the promotion of disease modeling and drug …
3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes
The blood-brain barrier (BBB) regulates molecular trafficking, protects against pathogens,
and prevents efficient drug delivery to the brain. Models to date failed to reproduce the …
and prevents efficient drug delivery to the brain. Models to date failed to reproduce the …
[HTML][HTML] Emergence of microfluidics for next generation biomedical devices
The attention in lab-on-a-chip devices with their potent application in medical engineering
has prolonged swiftly over the last ten years. Travelling through the technology …
has prolonged swiftly over the last ten years. Travelling through the technology …
3D printed microfluidic devices: a review focused on four fundamental manufacturing approaches and implications on the field of healthcare
In the last few years, 3D printing has emerged as a promising alternative for the fabrication
of microfluidic devices, overcoming some of the limitations associated with conventional soft …
of microfluidic devices, overcoming some of the limitations associated with conventional soft …