Cardiovascular diseases (CVD) are the number one cause of morbidity and death
worldwide. As estimated by the WHO, the global death rate from CVD is 31% wherein, a …

Tissue engineered vascular grafts (TEVGs) are beginning to achieve clinical success and
hold promise as a source of grafting material when donor grafts are unsuitable or …

Platelet adhesion is an essential function in response to vascular injury and is generally
viewed as the first step during which single platelets bind through specific membrane …

© SIMTI Servizi Srl von Willebrand factor (VWF) is an adhesive and multimeric glycoprotein
that found its historical origin in 1924, when the Finnish physician Erik von Willebrand first …

The adhesive protein von Willebrand factor (VWF) contributes to platelet function by
mediating the initiation and progression of thrombus formation at sites of vascular injury. In …

In this study we have examined the mechanism of platelet aggregation under physiological
flow conditions using an in vitro flow-based platelet aggregation assay and an in vivo rat …

Platelet-adhesive mechanisms play a well-defined role in hemostasis and thrombosis, but
evidence continues to emerge for a relevant contribution to other pathophysiological …

Fibrosis of visceral organs such as the lungs, heart, kidneys and liver remains a major cause
of morbidity and mortality and is also associated with many other disorders, including cancer …

The adhesive protein von Willebrand factor mediates the initiation and progression of
thrombus formation at sites of vascular injury. von Willebrand factor is synthesized in …

The reader will find here a concise summary of established notions on the structure and
function of von Willebrand factor (vWF), followed by a brief discussion of selected recent …