Drug repurposing: a promising tool to accelerate the drug discovery process

V Parvathaneni, NS Kulkarni, A Muth, V Gupta - Drug discovery today, 2019 - Elsevier
Highlights•There is an emerging need for new therapies for rare diseases in a shorter time
frame.•Drug repurposing could arise from serendipitous observations or exploiting side …

[HTML][HTML] Utilizing social media data for pharmacovigilance: a review

A Sarker, R Ginn, A Nikfarjam, K O'Connor… - Journal of biomedical …, 2015 - Elsevier
Abstract Objective Automatic monitoring of Adverse Drug Reactions (ADRs), defined as
adverse patient outcomes caused by medications, is a challenging research problem that is …

Cardiovascular adverse events reported from COVID-19 vaccines: a study based on WHO database

R Jeet Kaur, S Dutta, J Charan… - … journal of general …, 2021 - Taylor & Francis
Background Thirteen COVID-19 vaccines are granted emergency approval. It is crucial to
monitor their adverse events post vaccination. The present study focuses on cardiovascular …

Pharmacovigilance from social media: mining adverse drug reaction mentions using sequence labeling with word embedding cluster features

A Nikfarjam, A Sarker, K O'connor… - Journal of the …, 2015 - academic.oup.com
Objective Social media is becoming increasingly popular as a platform for sharing personal
health-related information. This information can be utilized for public health monitoring tasks …

–Omic and electronic health record big data analytics for precision medicine

PY Wu, CW Cheng, CD Kaddi… - IEEE Transactions …, 2016 - ieeexplore.ieee.org
Objective: Rapid advances of high-throughput technologies and wide adoption of electronic
health records (EHRs) have led to fast accumulation of-omic and EHR data. These …

Information retrieval and text mining technologies for chemistry

M Krallinger, O Rabal, A Lourenco, J Oyarzabal… - Chemical …, 2017 - ACS Publications
Efficient access to chemical information contained in scientific literature, patents, technical
reports, or the web is a pressing need shared by researchers and patent attorneys from …

[HTML][HTML] Portable automatic text classification for adverse drug reaction detection via multi-corpus training

A Sarker, G Gonzalez - Journal of biomedical informatics, 2015 - Elsevier
Objective Automatic detection of adverse drug reaction (ADR) mentions from text has
recently received significant interest in pharmacovigilance research. Current research …

[图书][B] Clinical text mining: Secondary use of electronic patient records

H Dalianis - 2018 - library.oapen.org
Hercules Dalianis Secondary Use of Electronic Patient Records Page 1 Hercules Dalianis
Clinical Text Mining Secondary Use of Electronic Patient Records Page 2 Clinical Text …

Computational drug repositioning: from data to therapeutics

MR Hurle, L Yang, Q Xie, DK Rajpal… - Clinical …, 2013 - Wiley Online Library
Traditionally, most drugs have been discovered using phenotypic or target‐based screens.
Subsequently, their indications are often expanded on the basis of clinical observations …

Text mining for adverse drug events: the promise, challenges, and state of the art

R Harpaz, A Callahan, S Tamang, Y Low, D Odgers… - Drug safety, 2014 - Springer
Text mining is the computational process of extracting meaningful information from large
amounts of unstructured text. It is emerging as a tool to leverage underutilized data sources …