Alzheimer's disease (AD) is the most common type of dementia, affecting more than 5 million
Americans, with steadily increasing mortality and incredible socio-economic burden. Not …

Clinical observations and preclinical studies both suggest that Down syndrome (DS) may be
associated with significant metabolic and bioenergetic alterations. However, the relevant …

Simple Summary Recently, immunotherapy has presented new opportunities for clinical
development in the treatment of non-small cell lung cancer (NSCLC). Although effective in …

The Down syndrome (DS) phenotype is usually characterized by relative strengths in non-
verbal skills and deficits in verbal processing, but high interindividual variability has been …

Down Syndrome (DS) is the most common genetic alteration responsible for intellectual
disability, which refers to deficits in both intellectual and adaptive functioning. According to …

Down syndrome (DS) or trisomy 21 is the most common genetic cause of intellectual
disability (ID), but a pathogenic mechanism has not been identified yet. Studying a complex …

Purpose/Objective: Although the concept of quality of life (QoL) has become a reference
framework for the provision of support and services to people with intellectual disability (ID) …

This work investigates the role of metabolite levels in the intellectual impairment of subjects
with Down syndrome (DS). Homocysteine, folate, vitamin B12, uric acid (UA), creatinine …

The Zika virus (ZIKV) can be vertically transmitted, causing congenital Zika syndrome (CZS)
in fetuses. ZIKV infection in early gestational trimesters increases the chances of developing …

Introduction Trisomy 21 (T21), which causes Down syndrome (DS), is the most common
chromosomal aneuploidy in humankind and includes different clinical comorbidities, among …