In this review, we consider affective cognition, responses to emotional stimuli occurring in
the context of cognitive evaluation. In particular, we discuss emotion categorization, biasing …

Depression is a leading cause of disability worldwide and improving its treatment is a core
research priority for future programmes. A change in the view of psychological and …

The fact that selective serotonin reuptake inhibitors (SSRIs) have antidepressant effects in
some patients supports the notion that serotonin plays a role in the mode of action of …

Impulsivity is common in Parkinson's disease even in the absence of impulse control
disorders. It is likely to be multifactorial, including a dopaminergic 'overdose'and structural …

The psychological mechanisms by which antidepressant drugs act to improve mood remain
underspecified. In this paper we consider the evidence to suggest that early changes in …

Overgeneralization (ie, the transfer of fear to stimuli not related to an aversive event) is part
of alterations in associative fear learning in mental disorders. In the present experimental …

Current antidepressant agents are similar in efficacy to the original drugs discovered in the
1950s. The development of new treatments for depression is, however, limited by the …

Rationale Lithium remains the most effective treatment for bipolar disorder and also has
important effects to lower suicidal behaviour, a property that may be linked to its ability to …

The subjective measures used to study mood disorders in humans cannot be replicated in
animals; however, the increasing application of objective neuropsychological methods …

Background5-HT4 receptor stimulation has pro-cognitive and antidepressant-like effects in
animal experimental studies; however, this pharmacological approach has not yet been …