Iron is an essential micronutrient that is problematic for biological systems since it is toxic as
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …

Interest in characterizing the role of impaired insulin actions in Alzheimer's disease (AD) and
vascular dementia is growing exponentially. This review details what is currently known …

Given the critical role of mitogen-activated protein kinase (MAPK) pathways in regulating
cellular processes that are affected in Alzheimer's disease (AD), the importance of MAPKs in …

Recent clinical research has demonstrated that berry fruits can prevent age-related
neurodegenerative diseases and improve motor and cognitive functions. The berry fruits are …

In Alzheimer's disease (AD), chronically activated glia contribute to neuronal dysfunction
through production of neuroinflammatory molecules like interleukin (IL)-1β. As a first step to …

The extracellular signal regulated protein kinases (ERK1/2) are essential for normal
development and functional plasticity of the central nervous system. However, a growing …

Increased oxidative stress and mitochondrial dysfunction have been identified as common
pathophysiological phenomena associated with neurodegenerative disorders such as …

Parkinson's disease (PD) is characterized by the selective loss of dopaminergic nigrostriatal
neurons, which leads to disabling motor disturbances. Sulforaphane (SFN), found in …

Alzheimer's disease (AD), Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS)
are the most common human adult-onset neurodegenerative diseases. They are …

purpose. Erythropoietin (EPO) modulates erythropoiesis by inhibiting apoptosis in
erythrocyte progenitors. Recently, EPO has been shown to be protective in experimental …