Use of ctDNA in early breast cancer: analytical validity and clinical potential

F Panet, A Papakonstantinou, M Borrell, J Vivancos… - npj Breast …, 2024 - nature.com
Circulating free tumor DNA (ctDNA) analysis is gaining popularity in precision oncology,
particularly in metastatic breast cancer, as it provides non-invasive, real-time tumor …

Molecular phenotyping of small cell lung cancer using targeted cfDNA profiling of transcriptional regulatory regions

JB Hiatt, AL Doebley, HU Arnold, M Adil… - Science …, 2024 - science.org
We report an approach for cancer phenotyping based on targeted sequencing of cell-free
DNA (cfDNA) for small cell lung cancer (SCLC). In SCLC, differential activation of …

Circulating Tumor DNA in Genitourinary Cancers: Detection, Prognostics, and Therapeutic Implications

MB Gerke, CS Jansen, MA Bilen - Cancers, 2024 - mdpi.com
Simple Summary Circulating tumor DNA (ctDNA) is a non-invasive method of identifying and
monitoring genitourinary cancers, including prostate, bladder, and renal cell carcinoma, via …

Machine learning-based detection of bladder cancer by urine cfDNA fragmentation hotspots that capture cancer-associated molecular features

XY Meng, XH Zhou, S Li, MJ Shi, XH Li… - Clinical …, 2024 - academic.oup.com
Background cfDNA fragmentomics-based liquid biopsy is a potential option for noninvasive
bladder cancer (BLCA) detection that remains an unmet clinical need. Methods We …

Recent advances in the use of liquid biopsy for the diagnosis and treatment of lung cancer

V Gristina, G Russo, TD Bazan Russo… - Expert Review of …, 2024 - Taylor & Francis
Introduction In the era of precision medicine, liquid biopsy rapidly emerges as an integrative
diagnostic tool to successfully stratify solid tumor patients in accordance with molecular …

Personalized Medicine: Leave no Patient Behind; Report From the 2024 Coffey‐Holden Prostate Cancer Academy Meeting

AK Miyahira, M Sharifi, LN Chesner, A El‐Kenawi… - The …, 2024 - Wiley Online Library
ABSTRACT Introduction The 11th Annual 2024 Coffey‐Holden Prostate Cancer Academy
(CHPCA) Meeting, was themed “Personalized Medicine: Leave No Patient Behind,” and was …

[HTML][HTML] Circulating Tumor DNA in Early and Metastatic Breast Cance—Current Role and What Is Coming Next

CM Tegeler, AD Hartkopf, M Banys-Paluchowski… - …, 2024 - pmc.ncbi.nlm.nih.gov
The progress that has been made in recent years in relation to liquid biopsies in general and
circulating tumor DNA (ctDNA) in particular can be seen as groundbreaking for the future of …

Elements of liquid biopsies: isolation, analysis and clinical application in cancer diagnosis to prognosis

NM Kumar, N Navaneeth, A Shettar… - Expert Review of …, 2024 - Taylor & Francis
Introduction The liquid biopsy is a breakthrough in the field of medical diagnostics. It serves
as a sentinel that can quietly detect even the subtlest aberrations that indicate the presence …

[HTML][HTML] Machine Learning Approaches in Multi-Cancer Early Detection

M Hajjar, S Albaradei, G Aldabbagh - Information, 2024 - mdpi.com
Cancer is a prominent global cause of mortality, primarily due to delayed detection leading
to limited treatment options. Current screening methods are mostly invasive and involve …

The Role of Artificial Intelligence in Early Cancer Detection: Exploring Early Clinical Applications

NG Thaker, AP Dicker, A Loaiza-Bonilla… - AI in Precision …, 2024 - liebertpub.com
Introduction: Early cancer detection can lead to improved outcomes and a shift toward a
prevention model. This review explores the role of artificial intelligence (AI) in early cancer …