Circular RNAs (circRNAs), one type of non-coding RNA, were initially misinterpreted as
nonfunctional products of pre-mRNA mis-splicing. Currently, circRNAs have been proven to …

Targeted treatment, which can specifically kill tumour cells without affecting normal cells, is a
new approach for tumour therapy. However, tumour cells tend to acquire resistance to …

Background Cisplatin (DDP) is the first-line chemotherapeutic drug for non-small cell lung
cancer (NSCLC), and long-term DDP stimulation increased resistance of NSCLC cells to this …

Membrane vesicles having a diameter of 30–150 nm are known as exosomes. Several
cancer types secrete exosomes, which may contain proteins, circular RNAs (circRNAs) …

Abstract circular RNA ciRS-7 (ciRS-7) is a type of endogenous circular RNA (circRNA) with a
closed circular structure. Since Hansen first demonstrated that ciRS-7 could serve as a …

Chemotherapy resistance typically leads to tumour recurrence and is a major obstacle to
cancer treatment. Increasing numbers of circular RNAs (circRNAs) have been confirmed to …

Circular RNAs (circRNAs) are covalently closed circular structures without 5′ caps and 3′
tails, which are mainly formed from precursor mRNAs (pre-mRNAs) via back-splicing of …

Circular RNAs (circRNAs) as a new class of non-coding RNAs (ncRNAs) play role in gene
regulation in multicellular organisms via various interactions with nucleic acids, proteins and …

Circular RNAs (circRNAs) are a type of single-stranded RNA molecules forming a covalently
closed, continuous structure, lacking 5′-3′ polarity and polyadenylated tails. Recent …

Lung cancer holds the highest mortality rate among malignancies worldwide. Nevertheless,
the potential molecular mechanisms of its tumorigenesis and evolution remain obscure …