Since its introduction to organic synthesis in 1977 by Kagan, 1, 2 samarium (II) iodide (SmI2,
Kagan's reagent) has gained the status of one of the most versatile single-electron transfer …

The principle of vinylogy states that the electronic effects of a functional group in a molecule
are possibly transmitted to a distal position through interposed conjugated multiple bonds …

Four decades since Mukaiyama's first reports on the successful application of silicon and
boron enolates in directed aldol reactions, the ability of this highly controlled carbon–carbon …

A one-pot protocol for the asymmetric α-allylation reaction is reported relying on a key
efficient asymmetric Claisen rearrangement, triggered by electrophilic activation of chiral …

Natural product synthesis remains a field in which new synthetic methods and reagents are
continually being evaluated. Due to the demanding structures and complex functionality of …

Covering: selected examples in the past three decades (up to 2018) The challenging
structures and often potent biological activities of naturally occurring macrocycles have …

This review collects the most important developments in asymmetric Reformatsky-type
reactions published since the beginning of 2013, including both diastereoselective …

In conjugated π systems, π-extended enolates generated in situ from unsaturated
pronucleophiles through suitable HOMO-raising strategies tend to proceed via …

The first total syntheses of (±)-catellatolactams A and B, two novel ansamacrolactams, are
described in 5 and 8 steps, respectively. The strategy relies on an amidation reaction to …

The assignment of absolute configuration (AC) is a crucial step in the structural
characterization of natural products, especially for those subjected to biological assays …