On the role of paraoxonase-1 and chemokine ligand 2 (CC motif) in metabolic alterations linked to inflammation and disease. A 2021 update

J Camps, H Castañé, E Rodríguez-Tomàs… - Biomolecules, 2021 - mdpi.com
Infectious and many non-infectious diseases share common molecular mechanisms. Among
them, oxidative stress and the subsequent inflammatory reaction are of particular note …

Resolvin D1 prevents injurious neutrophil swarming in transplanted lungs

W Li, HM Shepherd, Y Terada… - Proceedings of the …, 2023 - National Acad Sciences
Neutrophils are the primary cell type involved in lung ischemia-reperfusion injury (IRI), which
remains a frequent and morbid complication after organ transplantation. Endogenous lipid …

Primary graft dysfunction in lung transplantation: a review of mechanisms and future applications

L Chacon-Alberty, R Fernandez, P Jindra, M King… - …, 2023 - journals.lww.com
Lung allograft recipients have worse survival than all other solid organ transplant recipients,
largely because of primary graft dysfunction (PGD), a major form of acute lung injury …

Reprogramming alveolar macrophage responses to TGF-β reveals CCR2+ monocyte activity that promotes bronchiolitis obliterans syndrome

Z Liu, F Liao, J Zhu, D Zhou, GS Heo… - The Journal of …, 2022 - Am Soc Clin Investig
Bronchiolitis obliterans syndrome (BOS) is a major impediment to lung transplant survival
and is generally resistant to medical therapy. Extracorporeal photophoresis (ECP) is an …

Salidroside postconditioning attenuates ferroptosis-mediated lung ischemia-reperfusion injury by activating the Nrf2/SLC7A11 signaling axis

Y Wang, Z Chen, J Luo, J Zhang, A Sang… - International …, 2023 - Elsevier
Background Ferroptosis, an iron-dependent programmed necrosis, is linked to lung
ischemia–reperfusion injury. Salidroside is a glycoside derived from the Rhodiola rosea …

Crystalline silica-induced proinflammatory interstitial macrophage recruitment through notch3 signaling promotes the pathogenesis of silicosis

H Yuan, Y You, Y He, Y Wei, Y Zhang… - Environmental …, 2023 - ACS Publications
Crystalline silica (CS) particles are ubiquitous in the environment, especially in occupational
conditions, and exposure to respirable CS causes silicosis. The initial response to CS is …

Updated views on neutrophil responses in ischemia–reperfusion injury

HM Shepherd, JM Gauthier, Y Terada, W Li… - …, 2022 - journals.lww.com
Ischemia–reperfusion injury is an inevitable event during organ transplantation and
represents a primary risk factor for the development of early graft dysfunction in lung, heart …

Interorgan communication networks in the kidney–lung axis

Y Komaru, YZ Bai, D Kreisel, A Herrlich - Nature Reviews Nephrology, 2024 - nature.com
The homeostasis and health of an organism depend on the coordinated interaction of
specialized organs, which is regulated by interorgan communication networks of circulating …

Advances in lung ischemia/reperfusion injury: unraveling the role of innate immunity

Q Li, H Nie - Inflammation Research, 2024 - Springer
Background Lung ischemia/reperfusion injury (LIRI) is a common occurrence in clinical
practice and represents a significant complication following pulmonary transplantation and …

B cells mediate lung ischemia/reperfusion injury by recruiting classical monocytes via synergistic B cell receptor/TLR4 signaling

K Farahnak, YZ Bai, Y Yokoyama… - The Journal of …, 2024 - Am Soc Clin Investig
Ischemia/reperfusion injury–mediated (IRI-mediated) primary graft dysfunction (PGD)
adversely affects both short-and long-term outcomes after lung transplantation, a procedure …