Traumatic spinal cord injury: an overview of pathophysiology, models and acute injury mechanisms
A Alizadeh, SM Dyck, S Karimi-Abdolrezaee - Frontiers in neurology, 2019 - frontiersin.org
Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial
socioeconomic implications for patients and their care-givers. Recent advances in medical …
socioeconomic implications for patients and their care-givers. Recent advances in medical …
Pathogenic mechanisms following ischemic stroke
Stroke is the second most common cause of death and the leading cause of disability
worldwide. Brain injury following stroke results from a complex series of pathophysiological …
worldwide. Brain injury following stroke results from a complex series of pathophysiological …
An enzyme‐mimicking single‐atom catalyst as an efficient multiple reactive oxygen and nitrogen species scavenger for sepsis management
Sepsis, characterized by immoderate production of multiple reactive oxygen and nitrogen
species (RONS), causes high morbidity and mortality. Despite progress made with …
species (RONS), causes high morbidity and mortality. Despite progress made with …
The biology of ergothioneine, an antioxidant nutraceutical
Ergothioneine (ERG) is an unusual thio-histidine betaine amino acid that has potent
antioxidant activities. It is synthesised by a variety of microbes, especially fungi (including in …
antioxidant activities. It is synthesised by a variety of microbes, especially fungi (including in …
The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …
DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …
during the reoxygenation phase following hypoxia, is well known in a variety of acute …
Secondary injury mechanisms in traumatic spinal cord injury: a nugget of this multiply cascade
C Oyinbo - Acta neurobiologiae experimentalis, 2011 - ane.pl
The pathophysiology of acute spinal cord injury (SCI) involves primary and secondary
mechanisms of injury. Though both mechanisms are involved in the neurological …
mechanisms of injury. Though both mechanisms are involved in the neurological …
Sustainable Nanosheet Antioxidants for Sepsis Therapy via Scavenging Intracellular Reactive Oxygen and Nitrogen Species
Sepsis is an aberrant systemic inflammatory response mediated by excessive production of
reactive oxygen species (ROS) and reactive nitrogen species (RNS). Developing an efficient …
reactive oxygen species (ROS) and reactive nitrogen species (RNS). Developing an efficient …
Inflammatory mechanisms in ischemic stroke: therapeutic approaches
SE Lakhan, A Kirchgessner, M Hofer - Journal of translational medicine, 2009 - Springer
Acute ischemic stroke is the third leading cause of death in industrialized countries and the
most frequent cause of permanent disability in adults worldwide. Despite advances in the …
most frequent cause of permanent disability in adults worldwide. Despite advances in the …
Nox enzymes and new thinking on reactive oxygen: a double-edged sword revisited
JD Lambeth, AS Neish - Annual Review of Pathology …, 2014 - annualreviews.org
Reactive oxygen species (ROS) are a chemical class of molecules that have generally been
conceptualized as deleterious entities, albeit ones whose destructive properties could be …
conceptualized as deleterious entities, albeit ones whose destructive properties could be …
Nitric oxide and peroxynitrite in health and disease
P Pacher, JS Beckman, L Liaudet - Physiological reviews, 2007 - journals.physiology.org
The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …