Over the past decades, the number of patients with dry eye disease (DED) has increased
dramatically. The incidence of DED is higher in Asia than in Europe and North America …

Aims Oral mucosal diseases can lead to pain, difficulty speaking and eating, psychological
distress, and cancer. Topical drug delivery using biological macromolecules, specifically …

Dry eye disease is a chronic condition of the corneal surface marked by persistent symptoms
of irritation or burning that can cause inflammatory damage to the cornea and conjunctiva if …

Purpose: Dry eye is a major ocular pathology worldwide. Although dry eye is a multifactorial
disease, recent studies have shown that chronic immunologic processes have a pivotal role …

The core mechanism of dry eye is the tear film instability. Tear film-oriented diagnosis
(TFOD) is a concept to clarify the cause of tear film instability by tear film, and tear film …

The 2017 consensus report of the Asia Dry Eye Society (ADES) on the definition and
diagnosis of dry eyes described dry eye disease as “Dry eye is a multifactorial disease …

The definition and diagnostic criteria of dry eye disease (DED) proposed by the Japan Dry
Eye Society and other countries are reviewed. The first definition and criteria of DED in …

Purpose To evaluate the efficacy and safety of intense pulsed light (IPL) combined with
meibomian gland expression (MGX) for treatment of refractory meibomian gland dysfunction …

Dry eye disease (DED) is among the most common eye diseases and is becoming
increasingly prevalent. Its symptoms cause a long-term decline in patients' health-related …

Lactoferrin (LF) is one of the major functional proteins in maintaining human health due to its
antioxidant, antibacterial, antiviral, and anti-inflammatory activities. Abnormal levels of LF in …