Steroidogenesis, the processes by which cholesterol is converted to steroid hormones,
involves transport proteins, enzymes, redox partners and cofactors. Most steroidogenic …

More than 90% of cases of congenital adrenal hyperplasia (CAH, the inherited inability to
synthesize cortisol) are caused by 21-hydroxylase deficiency. Females with severe, classic …

Background—In obesity, the excessive synthesis of aldosterone contributes to the
development and progression of metabolic and cardiovascular dysfunctions. Obesity …

Steroid hormone biosynthesis in steroidogenic cells is regulated through trophic hormone
activation of protein kinase A (PKA) signaling pathways. However, many examples of the …

Spät, András, and László Hunyady. Control of Aldosterone Secretion: A Model for
Convergence in Cellular Signaling Pathways. Physiol Rev 84: 489–539, 2004; …

Aldosterone is the major mineralocorticoid synthesized by the adrenal and plays an
important role in the regulation of systemic blood pressure through the absorption of sodium …

In the 60 years that have passed since the discovery of the mineralocorticoid hormone
aldosterone, much has been learned about its synthesis (both adrenal and extra-adrenal) …

A. Single-transmembrane segment receptors B. Seven-transmembrane receptors C. Steroid
hormones D. Intracellular second messengers IV. Cyclins and CKIs in Endocrine Tumors A …

Aldosterone is a steroid hormone synthesized in and secreted from the outer layer of the
adrenal cortex, the zona glomerulosa. Aldosterone is responsible for regulating sodium …

I. Introduction T HE OVARY and testis share homology of structure and function in the
production of gametes and in the regulation of steroidogenesis. The dependence of …