Chemodynamic therapy (CDT) uses the tumor microenvironment‐assisted intratumoral
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …

Patient-derived xenograft (PDX) models, in which tumor tissues from patients are implanted
into immunocompromised or humanized mice, have shown superiority in recapitulating the …

Chemodynamic therapy (CDT) is an emerging therapy method that kills cancer cells by
converting intracellular hydrogen peroxide (H2O2) into highly toxic hydroxyl radicals (• OH) …

Due to the rapid proliferation of tumors, the hydrogen peroxide (H 2 O 2) concentration of
tumor cells is higher than that of normal cells, which can be used as an effective target for …

Hypoxia, a hallmark of solid tumors, determines the selection of invasive and aggressive
malignant clones displaying resistance to radiotherapy, conventional chemotherapy or …

Chemodynamic therapy (CDT) is a novel therapeutic modality that employs Fenton or
Fenton-like reactions to destroy cancer cells via the disproportionation of intratumoral …

Radiotherapy (RT) uses ionizing radiation to eradicate localized tumors and, in rare cases,
control tumors outside of the irradiated fields via stimulating an antitumor immune response …

The immune checkpoint blockade (ICB) therapy has revolutionized the field of cancer
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …

Cancer immunotherapies, such as immune checkpoint blockade and chimeric antigen
receptor (CAR) T cell therapy, have transformed clinical oncology. However, limited patient …

Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …