Mechanisms of 3D cell migration
KM Yamada, M Sixt - Nature Reviews molecular cell biology, 2019 - nature.com
Cell migration is essential for physiological processes as diverse as development, immune
defence and wound healing. It is also a hallmark of cancer malignancy. Thousands of …
defence and wound healing. It is also a hallmark of cancer malignancy. Thousands of …
Mechanics of 3D cell–hydrogel interactions: experiments, models, and mechanisms
Hydrogels are highly water-swollen molecular networks that are ideal platforms to create
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …
Focal adhesion–independent cell migration
EK Paluch, IM Aspalter, M Sixt - Annual review of cell and …, 2016 - annualreviews.org
Cell migration is central to a multitude of physiological processes, including embryonic
development, immune surveillance, and wound healing, and deregulated migration is key to …
development, immune surveillance, and wound healing, and deregulated migration is key to …
[HTML][HTML] The role and regulation of blebs in cell migration
Blebs are cellular protrusions that have been shown to be instrumental for cell migration in
development and disease. Bleb expansion is driven by hydrostatic pressure generated in …
development and disease. Bleb expansion is driven by hydrostatic pressure generated in …
Intracellular fluid mechanics: Coupling cytoplasmic flow with active cytoskeletal gel
A Mogilner, A Manhart - Annual Review of Fluid Mechanics, 2018 - annualreviews.org
The cell is a mechanical machine, and continuum mechanics of the fluid cytoplasm and the
viscoelastic deforming cytoskeleton play key roles in cell physiology. We review …
viscoelastic deforming cytoskeleton play key roles in cell physiology. We review …
Supracellular migration–beyond collective cell migration
A Shellard, R Mayor - Journal of cell science, 2019 - journals.biologists.com
Collective cell migration is a highly complex process in which groups of cells move together.
A fundamental question is how cell ensembles can migrate efficiently. In some cases, the …
A fundamental question is how cell ensembles can migrate efficiently. In some cases, the …
Glioblastoma Spheroid Invasion through Soft, Brain‐Like Matrices Depends on Hyaluronic Acid–CD44 Interactions
G Safarians, A Sohrabi, I Solomon… - Advanced …, 2023 - Wiley Online Library
Increased secretion of hyaluronic acid (HA), a glycosaminoglycan abundant in the brain
extracellular matrix (ECM), correlates with worse clinical outcomes for glioblastoma (GBM) …
extracellular matrix (ECM), correlates with worse clinical outcomes for glioblastoma (GBM) …
Actin filament structures in migrating cells
J Lehtimäki, M Hakala, P Lappalainen - The Actin Cytoskeleton, 2017 - Springer
Cell migration is necessary for several developmental processes in multicellular organisms.
Furthermore, many physiological processes such as wound healing and immunological …
Furthermore, many physiological processes such as wound healing and immunological …
[HTML][HTML] Amoeboid swimming is propelled by molecular paddling in lymphocytes
Mammalian cells developed two main migration modes. The slow mesenchymatous mode,
like crawling of fibroblasts, relies on maturation of adhesion complexes and actin fiber …
like crawling of fibroblasts, relies on maturation of adhesion complexes and actin fiber …
[HTML][HTML] Intracellular pressure dynamics in blebbing cells
W Strychalski, RD Guy - Biophysical journal, 2016 - cell.com
Blebs are pressure-driven protrusions that play an important role in cell migration,
particularly in three-dimensional environments. A bleb is initiated when the cytoskeleton …
particularly in three-dimensional environments. A bleb is initiated when the cytoskeleton …