Abstract Interleukin-18 (IL-18) is an immune-stimulatory cytokine with antitumor activity in
preclinical models. It plays pivotal roles in linking inflammatory immune responses and …

IL-12 and IL-18 are immunomodulatory cytokines that play important roles in host immune
response against cancers. Variation in DNA sequence in gene promoter may lead to altered …

Abstract Interleukin-18 (IL-18) is a pleiotropic, pro-inflammatory cytokine with dual effects on
tumor development and progression. The-607 (C/A) and-137 (G/C) polymorphisms in IL-18 …

Objectives To study the risk of polymorphisms present in the non-coding regions of genes
related with cervical cancer. Methods The PubMed database was extensively searched …

Cervical cancer is a leading women cancer globally with respect to both incidence and
mortality. Its increased risk has been linked with HPV infection and genetic variations like …

Elevated lead absorptions are hazardous factors in lead-related workers. Previous studies
have found its toxic impacts on nervous, circulatory, and metabolic systems. We …

IFN-γ has a central role in the defense against infections and cancer. More recently,
however, IFN-γ has also been reported to have immunosuppressive effects in models of …

Inflammation is an important hallmark of all types of cancers with a well-established role in
carcinogenesis. The net inflammatory response is determined by the balance between pro …

Abstract Background: The Human Papillomavirus (HPV) predisposes 500 000 women to
cervical cancer. Host genetic background may facilitate virus persistence in the uterine …

Nasopharyngeal carcinoma (NPC) is one of the most common cancers in southern China. In
addition to environmental factors such as Epstein-Barr virus infection and chemical …