Because of the rise in antibiotic resistance and the dwindling pipeline of effective antibiotics,
it is imperative to explore avenues that breathe new life into existing drugs. This is …

The emergence of antimicrobial resistance (AMR) is rapidly increasing and it is one of the
significant twenty-first century's healthcare challenges. Unfortunately, the development of …

β-lactam antibiotics are one of the most widely used and diverse classes of antimicrobial
agents for treating both Gram-negative and Gram-positive bacterial infections. The β-lactam …

There is a need to discover and develop non-toxic antibiotics that are effective against
metabolically dormant bacteria, which underlie chronic infections and promote antibiotic …

Antimicrobial peptides (AMPs) are pinpointed as promising molecules against antibiotic-
resistant bacterial infections. Nevertheless, there is a discrepancy between the AMP …

Gram-negative bacteria are intrinsically resistant to many classes of antibiotics,
predominantly due to the impermeability of the outer membrane and the presence of efflux …

Antimicrobial resistance (AMR) has been increasing unrelentingly worldwide, thus
negatively impacting human health. The discovery and development of novel antibiotics is …

Antibiotic resistance is a growing global problem that requires innovative therapeutic
approaches and strategies for administering antibiotics. One promising approach is …

Gram-negative strains are intrinsically resistant to most antibiotics due to the robust and
impermeable characteristic of their outer membrane. Self-assembling cationic peptide …

In view of the increased prevalence of antimicrobial resistance among human pathogens,
antibiotics against multidrug-resistant (MDR) bacteria are in urgent demand. In particular …