Chloroquine and sulfadoxine–pyrimethamine resistance in Sub-Saharan Africa—A review

AT Roux, L Maharaj, O Oyegoke, OP Akoniyon… - Frontiers in …, 2021 - frontiersin.org
Malaria is a great concern for global health and accounts for a large amount of morbidity and
mortality, particularly in Africa, with sub-Saharan Africa carrying the greatest burden of the …

Drug resistance markers within an evolving efficacy of anti-malarial drugs in Cameroon: a systematic review and meta-analysis (1998–2020)

PTN Niba, AM Nji, MS Evehe, IM Ali, PM Netongo… - Malaria Journal, 2021 - Springer
Background Malaria remains highly endemic in Cameroon. The rapid emergence and
spread of drug resistance was responsible for the change from monotherapies to artemisinin …

Antimalarial drug resistance in the Central and Adamawa regions of Cameroon: Prevalence of mutations in P. falciparum crt, Pfmdr1, Pfdhfr and Pfdhps genes

AGB Tuedom, EM Sarah-Matio, CEE Moukoko… - PLoS …, 2021 - journals.plos.org
The spread of Plasmodium falciparum resistant parasites remains one of the major
challenges for malaria control and elimination in Sub Saharan Africa. Monitoring of …

Epidemiology of malaria and chloroquine resistance in Mizoram, northeastern India, a malaria-endemic region bordering Myanmar

R Zomuanpuii, CL Hmar, K Lallawmzuala, L Hlimpuia… - Malaria journal, 2020 - Springer
Background Mizoram, a northeastern state in India, shares international borders with
Myanmar and Bangladesh and is considered to be one of the key routes through which drug …

Assessment of molecular markers of anti-malarial drug resistance among children participating in a therapeutic efficacy study in western Kenya

W Chebore, Z Zhou, N Westercamp, K Otieno, YP Shi… - Malaria Journal, 2020 - Springer
Background Anti-malarial drug resistance remains a major threat to global malaria control
efforts. In Africa, Plasmodium falciparum remains susceptible to artemisinin-based …

Genome-wide genetic variation and molecular surveillance of drug resistance in Plasmodium falciparum isolates from asymptomatic individuals in Ouélessébougou …

LN Vanheer, A Mahamar, E Manko, SM Niambele… - Scientific Reports, 2023 - nature.com
Sequence analysis of Plasmodium falciparum parasites is informative in ensuring sustained
success of malaria control programmes. Whole-genome sequencing technologies provide …

The return of chloroquine-sensitive Plasmodium falciparum parasites in Jazan region, southwestern Saudi Arabia over a decade after the adoption of artemisinin-based …

AM Madkhali, AA Abdulhaq, WM Atroosh… - Parasitology …, 2021 - Springer
This study investigated the polymorphism in the P. falciparum chloroquine resistance
transporter (pfcrt) gene 11 years after chloroquine (CQ) cessation in Jazan region …

[HTML][HTML] Polymorphisms in Plasmodium falciparum chloroquine resistance transporter (Pfcrt) and multidrug-resistant gene 1 (Pfmdr-1) in Nigerian children 10 years …

AT Kayode, K Akano, FV Ajogbasile… - International journal for …, 2021 - Elsevier
The emergence and spread of Plasmodium falciparum parasites resistant to artemisinin
derivatives and their partners in southeastern Asia threatens malaria control and elimination …

Efficacy of artemether-lumefantrine and artesunate-amodiaquine as first line therapy of uncomplicated malaria in Burkina Faso, 11 years after policy change

I Zongo, YD Compaoré, F Nikiéma, M Zongo… - Pan African Medical …, 2020 - ajol.info
Abstract Introduction: artemether-lumefantrine (AL) and artesunate-amodiaquine (ASAQ) are
the first line therapy of uncomplicated malaria in Burkina Faso. We assessed the treatment …

On the contribution of the rodent model Plasmodium chabaudi for understanding the genetics of drug resistance in malaria

P Cravo - Parasitology International, 2022 - Elsevier
Malaria is a devastating disease that still claims over half a million lives every year, mostly in
sub–Saharan Africa. One of the main barriers to malaria control is the evolution and …