Alcohol dehydrogenases, aldehyde dehydrogenases, and alcohol use disorders: a critical review
HJ Edenberg, JN McClintick - Alcoholism: Clinical and …, 2018 - Wiley Online Library
Alcohol use disorders (AUDs) are complex traits, meaning that variations in many genes
contribute to the risk, as does the environment. Although the total genetic contribution to risk …
contribute to the risk, as does the environment. Although the total genetic contribution to risk …
Alcohol-induced oxidative stress and the role of antioxidants in alcohol use disorder: a systematic review
EE Tsermpini, A Plemenitaš Ilješ, V Dolžan - Antioxidants, 2022 - mdpi.com
Alcohol use disorder (AUD) is a highly prevalent, comorbid, and disabling disorder. The
underlying mechanism of ethanol neurotoxicity and the involvement of oxidative stress is still …
underlying mechanism of ethanol neurotoxicity and the involvement of oxidative stress is still …
Genome-wide association study of alcohol dependence: significant findings in African-and European-Americans including novel risk loci
We report a GWAS of alcohol dependence (AD) in European-American (EA) and African-
American (AA) populations, with replication in independent samples of EAs, AAs and …
American (AA) populations, with replication in independent samples of EAs, AAs and …
Overview of the genetics of alcohol use disorder
EA Tawa, SD Hall, FW Lohoff - Alcohol and alcoholism, 2016 - academic.oup.com
Abstract Aims Alcohol Use Disorder (AUD) is a chronic psychiatric illness characterized by
harmful drinking patterns leading to negative emotional, physical, and social ramifications …
harmful drinking patterns leading to negative emotional, physical, and social ramifications …
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study
E Jorgenson, KK Thai, TJ Hoffmann, LC Sakoda… - Molecular …, 2017 - nature.com
Alcohol consumption is a complex trait determined by both genetic and environmental
factors, and is correlated with the risk of alcohol use disorders. Although a small number of …
factors, and is correlated with the risk of alcohol use disorders. Although a small number of …
The genetics of alcohol dependence and alcohol-related liver disease
The susceptibility to developing alcohol dependence and significant alcohol-related liver
injury is determined by a number of constitutional, environmental and genetic factors …
injury is determined by a number of constitutional, environmental and genetic factors …
Genetic studies of alcohol dependence in the context of the addiction cycle
Family, twin and adoption studies demonstrate clearly that alcohol dependence and alcohol
use disorders are phenotypically complex and heritable. The heritability of alcohol use …
use disorders are phenotypically complex and heritable. The heritability of alcohol use …
A decade in psychiatric GWAS research
After more than 10 years of accumulated efforts, genome-wide association studies (GWAS)
have led to many findings, most of which have been deposited into the GWAS Catalog …
have led to many findings, most of which have been deposited into the GWAS Catalog …
Human genetics of addiction: new insights and future directions
DB Hancock, CA Markunas, LJ Bierut… - Current psychiatry …, 2018 - Springer
Abstract Purpose of Review With the advent of the genome-wide association study (GWAS),
our understanding of the genetics of addiction has made significant strides forward. Here …
our understanding of the genetics of addiction has made significant strides forward. Here …
Alcohol dependence genetics: lessons learned from genome‐wide association studies (GWAS) and post‐GWAS analyses
AB Hart, HR Kranzler - Alcoholism: Clinical and Experimental …, 2015 - Wiley Online Library
Background Alcohol dependence (AD) is a complex psychiatric disorder and a significant
public health problem. Twin and family‐based studies have consistently estimated its …
public health problem. Twin and family‐based studies have consistently estimated its …