The first edition of Molecular Genetics of Mycobacteria (1) was published very shortly after
the release of the complete genome sequence of Mycobacterium tuberculosis H37Rv (2) …

As for all other organisms, life of bacterial pathogens has been subject to a selective
pressure to grow and multiply. For these bacteria, the host is a huge source of nutrients, and …

Objective: The aim of the present study was to explore the potential biological role of
Rv2629 in Mycobacterium smegmatis and Mycobacterium tuberculosis. Methods …

Uracil phosphoribosyltransferase (UPRT) catalyzes the conversion of uracil and 5-
phosphoribosyl-α-1-pyrophosphate (PRPP) to uridine 5′-monophosphate (UMP) and …

Administration of the current tuberculosis (TB) vaccine to newborns is not a reliable route for
preventing TB in adults. The conversion of XMP to GMP is catalyzed by guaA-encoded GMP …

The emergence of drug-resistant Mycobacterium tuberculosis (Mtb) stains has escalated the
need for developing more efficient drugs and therapeutic strategies against tuberculosis …

A continuous FeMo cofactor supply for nitrogenase maturation is ensured in Azotobacter
vinelandii by developing a cage‐like molybdenum storage protein (MoSto) capable to store …

The infection of the Burkholderia pseudomallei causes the disease melioidosis. for which
the treatment method takes longer time, and sometimes it is difficult to completely eradicate …

Enzymes from the nucleotide biosynthesis pathway are potential targets for the development
of novel anti-mycobacterial agents. Inosine 5′-monophosphate (IMP) dehydrogenase from …

In an attempt to find a new class of antitubercular agents, a series of 1, 2, 3, 6-
tetrahydropyrimidine-5-carbonitrile were prepared via the reaction of ethyl N …