Keratin 6, 16 and 17—critical barrier alarmin molecules in skin wounds and psoriasis
X Zhang, M Yin, L Zhang - Cells, 2019 - mdpi.com
Located at the skin surface, keratinocytes (KCs) are constantly exposed to external stimuli
and are the first responders to invading pathogens and injury. Upon skin injury, activated …
and are the first responders to invading pathogens and injury. Upon skin injury, activated …
Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia
HH Bragulla, DG Homberger - Journal of anatomy, 2009 - Wiley Online Library
Historically, the term 'keratin'stood for all of the proteins extracted from skin modifications,
such as horns, claws and hooves. Subsequently, it was realized that this keratin is actually a …
such as horns, claws and hooves. Subsequently, it was realized that this keratin is actually a …
Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies.
R Moll, A Löwe, J Laufer, WW Franke - The American journal of …, 1992 - ncbi.nlm.nih.gov
The authors have recently identified a new cytokeratin (CK) polypeptide, CK 20, whose
expression is almost entirely confined to the gastric and intestinal epithelium, urothelium …
expression is almost entirely confined to the gastric and intestinal epithelium, urothelium …
Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns.
R Moll, DL Schiller, WW Franke - The Journal of cell biology, 1990 - rupress.org
A major cytoskeletal polypeptide (Mr approximately 46,000; protein IT) of human intestinal
epithelium was characterized by biochemical and immunological methods. The polypeptide …
epithelium was characterized by biochemical and immunological methods. The polypeptide …
Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice.
R Vassar, M Rosenberg, S Ross… - Proceedings of the …, 1989 - National Acad Sciences
A construct containing approximately 2500 base pairs (bp) of 5'upstream and approximately
700 bp of 3'downstream sequence was used to drive the expression of an intronless human …
700 bp of 3'downstream sequence was used to drive the expression of an intronless human …
Elucidating the early stages of keratin filament assembly.
PA Coulombe, E Fuchs - The Journal of cell biology, 1990 - rupress.org
Because of extraordinarily tight coiled-coil associations of type I and type II keratins, the
composition and structure of keratin subunits has been difficult to determine. We report here …
composition and structure of keratin subunits has been difficult to determine. We report here …
Expression of keratin K14 in the epidermis and hair follicle: insights into complex programs of differentiation.
PA Coulombe, R Kopan, E Fuchs - The Journal of cell biology, 1989 - rupress.org
Keratins K14 and K5 have long been considered to be biochemical markers of the stratified
squamous epithelia, including epidermis (Moll, R., W. Franke, D. Schiller, B. Geiger, and R …
squamous epithelia, including epidermis (Moll, R., W. Franke, D. Schiller, B. Geiger, and R …
Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation.
A Stoler, R Kopan, M Duvic, E Fuchs - The Journal of cell biology, 1988 - rupress.org
We report here the isolation and characterization of three antisera, each of which is specific
for a single keratin from one of the three different pairs (K1/K10, K14/K5, K16/K6) that are …
for a single keratin from one of the three different pairs (K1/K10, K14/K5, K16/K6) that are …
The role of the basement membrane in differential expression of keratin proteins in epithelial cells
MA Kurpakus, EL Stock, JCR Jones - Developmental biology, 1992 - Elsevier
Extracellular matrix is considered to play an important role in determining the phenotype of
cells with which it interacts. Here we have investigated the possibility that extracellular matrix …
cells with which it interacts. Here we have investigated the possibility that extracellular matrix …
Identification of a tissue-specific putative transcription factor in breast tissue by serological screening of a breast cancer library
D Jäger, E Stockert, AO Güre, MJ Scanlan… - Cancer research, 2001 - AACR
Application of SEREX (serological analysis of recombinant tumor cDNA expression libraries)
to different tumor types has led to the identification of several categories of human tumor …
to different tumor types has led to the identification of several categories of human tumor …